Nobody downloaded yet

Hematology - Coursework Example

Comments (1) Cite this document
Neutrophils are granulocytes –white blood cells - produced by the bone marrow. There are about 1.3 x 1011 neutrophils per 80-kg person per day produced by hematopoietic system. Neutrophils contain primary (azurophilic) and secondary granules. …
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER95.8% of users find it useful
Read TextPreview

Extract of sample

Download file to see previous pages Neutrophils contain primary (azurophilic) and secondary granules. Primary granules contain a enzymes and molecules that play a role in killing microbes, including hydrolases, elastase, myeloperoxidase, cationic proteins, defensins, and bactericidal/permeability-increasing protein. Secondary granules contain unique molecules such as lactoferrin, vitamin B12–binding protein, NADPH oxidase (which produces hydrogen peroxide), and chemoattractants receptors. The nucleus of neutrophils normally contains up to four segments, which is why they are also known as polymorphonuclear (PMN) cells. Neutrophils are phagocytes that perform the functions of immune surveillance and in situ elimination of microorganisms and cell debris. They circulate in the blood and also line vascular endothelium. They are the first immune cells to arrive at the site of inflammation through chemotaxis, and rapidly extravasate into the surrounding tissues. In the tissues, they release the degradative enzymes in their secondary granules that kills bacteria but also causes tissue destruction. They carry out phagocytosis to engulf opsonized cell debris and microorganisms that they come in contact with. The vacuole with the phagocytosed organism is fused with the primary granules, causing the oxidative and antimicrobial enzymes to access and kill the ingested microorganism. Neutrophils self-destruct after a life of 1-4 days in tissues. - Lymphocyte There are two main types of lymphocytes: B cells and T cells. They are round cells with a large, round nucleus and scant cytoplasm. Lymphocytes govern the acquired arm of immunity, they are responsible for mounting a specific host immune response targeted against a particular invading organism. B cell precursors are produced in the bone marrow, but they migrate to the peripheral lymphoid organs, where they undergo maturation with antigen exposure to plasma cells. An important function of plasma cells is to produce immunoglobulins (Igs). A major function of immunoglobulins is to act as antibodies. Antibodies help degrade and clear foreign substances by binding to specific microorganisms’ molecules called antigens, a process termed opsonization, and produce specific results including antibody-mediated cellular toxicity and activation of the complement system that destroys foreign cells. There are hundreds of thousands of different B cells in the body at a time, each is capable of producing an immunoglobin specific to a microbe, this arsenal of B cells makes the body capable of mounting an antibody response against nearly every possible virus, bacteria, fungus and protozoa that can be encountered. T cells similarly undergo maturation in peripheral lymphoid organs and the thymus, they produce ‘T cell receptors’ specific to foreign microbes. Activation of T cells requires interaction of the T cell receptor with an antigen-presenting cell; activated T cells are responsible for delayed-type immunity. There are 2 main types of T cells: CD4 cells, called T helper cells, which produce cytokines that activate B cells (by IL-4 and IL-5), macrophages (by IFN-gamma) and other immune cells. CD8 cells, also called T cytotoxic cells, destroy cells with intracellular microorganisms such as M. tuberculosis, virus-infected cells, tumor cells and allografts. - Monocyte Monocytes are circulating agranulocytes with a kidney-shaped nucleus. They have two main functions: phagocytosis of microorganisms, and presentation of antigens to T cells to activate the acquired arm of immunity. They are released from the bone marrow and circulate in blood for about 72 hours before migrating into tissues to transform into macrophages to carry out their functions. They have surface receptors that can recognize bacteria, such as Toll-like ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Hematology Coursework Example | Topics and Well Written Essays - 1750 words”, n.d.)
Hematology Coursework Example | Topics and Well Written Essays - 1750 words. Retrieved from https://studentshare.org/biology/1439459-haematology-lab-questions
(Hematology Coursework Example | Topics and Well Written Essays - 1750 Words)
Hematology Coursework Example | Topics and Well Written Essays - 1750 Words. https://studentshare.org/biology/1439459-haematology-lab-questions.
“Hematology Coursework Example | Topics and Well Written Essays - 1750 Words”, n.d. https://studentshare.org/biology/1439459-haematology-lab-questions.
  • Cited: 0 times
Comments (1)
Click to create a comment or rate a document
emmykessler added comment 6 months ago
Student rated this paper as
I never thought 1750 words essay could be written in such a free manner. I loved the idea of this essay. Will definitely use it for my own work!
Biology Topic: Malaria: Why do so many people still die of Malaria
Malaria is an infectious disease caused by a parasite called Plasmodium that affects the red blood cells. Generally, chills, pain, fever, and sweating are the main symptoms of malaria. Parasites in human blood were firstly identified by C. Laveran in 1880 and subsequently in 1889; R.
8 Pages(2000 words)Coursework
Parallel Imaging. Advantages And Disadvantages Of Parallel Imaging
Parallel Imaging. Parallel imaging is a family of techniques that often take advantage of spatial information in phased-array of radiofrequency coils in reducing the acquisition times in the magnetic resonance imaging. Recent studies have indicated that in parallel imaging, the sampled k-space lines are often reduced by a factor equal or greater than two hence shortening acquisition times.
16 Pages(4000 words)Assignment
Indeed the stakeholders have been given scant respect and have been fooled perfectly, with the help of the external company auditors. Though the US government has indeed taken tough action against the Lehmann Brothers, through the process of asking for the explanation of the whole manipulation act from the CEO of the company, still nothing much could be achieved since the Lehman Company filed for bankruptcy in 2008.
1 Pages(250 words)Essay
The process of blood formation is known as hematopoiesis whereby cellular components of blood are derived from haematopoietic stem cells. This is facilitated by the ability of a cell to multiply to different types of cell a term commonly referred to as pluripotent.
2 Pages(500 words)Essay
Alder-Reilly anomaly is as a result of a defect involving complexes of protein-carbohydrate, which is termed as mucopolysaccharides (Hudnall 102). It is a rare disorder and autosomal
1 Pages(250 words)Assignment
Notably, marketing entails a customer centric culture and through such, an organization is able to identify new methods of reaching clients. The approach also engages
10 Pages(2500 words)Coursework
Write up of 'Cameroon Case Study'
It becomes visible at a minimum age of four months. The disease signs are linked to anaemia, pain, and disease`s complications. To diagnose sickle cell condition, it involved four screening test. That is, two haemolytic tests, one observation under a
5 Pages(1250 words)Coursework
Hemolytic anemia- This is a pathological condition associated with the decrease in the number of red blood cells due to the disruption of erythropoiesis and erythrocyte destruction. This is mainly prominent in the bone
1 Pages(250 words)Research Paper
Clinical Phlebotomy
A puncture is then made perpendicular to the ridges of the fingerprint. The first drop is wiped away, and the subsequent drops in the correct micro-tube. Gently the finger can be massaged to
5 Pages(1250 words)Coursework
Oncology, Hematology, Immunology
This kind of disease is much rare and it affects few adults in the world. The aim of this study is to find out the diagnosis of acute myeloid leukemia, signs and symptoms, care and management of the (AML), (Linnet 68).
1 Pages(250 words)Assignment
All About Malaria Coursework
The multiplication of these parasites takes place in liver and there after infects red blood cells. Though the normal way of malaria transmission is through mosquito bite, in rare case it is caused by transfusion of blood and from a pregnant mother to fetus (Griffith 2006, p.
4 Pages(1000 words)Coursework
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Coursework on topic Hematology for FREE!
logo footer
Contact us:
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us