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Wet Lab. Cellular Replacement Therapy And Stem Cell Research - Essay Example

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The discovery and isolation of stem cells proved to be a in the history of molecular biology, and the medical sciences that they inform. In addition to the obvious advantages of providing a clear model for embryonic development…
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Wet Lab. Cellular Replacement Therapy And Stem Cell Research
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"Wet Lab. Cellular Replacement Therapy And Stem Cell Research"

Download file to see previous pages When embryonic mouse stem cells were isolated more than 25 years ago, the significance of the discovery was soon realized. (Keller, 2005) there are many researchers and hold out hope for cellular replacement therapy arising from stem cell research. Specifically, embryonic stem cells, also known as ES - pluripotent cells are of great concern. They exhibit the potential to differentiate into a variety of final tissue types when they reach their ultimate, fully matured state. Embryonic stem cell lines are usually derived from a blastocyst, or in some cases an earlier stage of embryonic development. The 150 cells which at most comprise the blastocyst are able to differentiate into all types of body tissues. (Stem Cell Information, 2009) Most immediately, a pluripotent stem cell will give rise to the primary germ layers: ectoderm, mesoderm, and endoderm. From these layers, other cells and tissues differentiate but ultimately give rise to all internal organs of the future organism. (Scholer, 2007) Other types of stem cells, further in development also have uses in research and therapy; multipotent stem cells have some flexibility, but usually only within a closely related family of cells, such as cardiac tissue, blood cells. Furthermore, the cells can become Unipotent cells - which are not themselves per se, because they can only produce new cells of the exact same type. On the other end of the spectrum, are totipotent stem cells, these are fertilized zygotes which have the potential to grow into an entire individual, an embryonic stem cell from a blastocyst does not qualify.(Scholer, 2007) Cells can also be classified in terms of progenitor or precursor. Precursors exhibit recognizable traits of the function type they will become, while Progenitors are not outwardly committed to a cell type. (Rabbany et al. 2003) An extensive variety of proteins are responsible for differentiation of which much more research is needed. We are only now discovering the functions of regulatory operators such as Shp2, or transforming growth factor-?, that aids in the expression of chorionic gonadotropin.(Burnham Institute, 2009), (Keller, 2005) A well-studied pathway is the process of hematopoiesis, by which stem cells give rise to various types of blood cells. (Mackey, 2001) There are essentially two branches to the hematopoietic differentiation process: the lineage beginning with a myeloid progenitor, and the lineage stemming from the common lymphoid progenitor. (Parslow et al. 1997) The lymphoid progenitor arises from the multi-potential Hemocytoblast. The lymphoid progenitor differentiates into what are described as T cells. Differentiation is possible into the natural killer cells, CD4 and CD8 types, known as large granular lymphocytes, from which no further cell lines arise. But the lymphoid progenitor can also become the small lymphocyte. This stem cell has the potential to become a T-lymphocyte helper cell, or a B lymphocyte, which can further differentiate into plasma cells from which antibodies are produced. (Leishman et al. 2001), (Obeyesekere et al. 2004) But the hemocytoblast from which these types arise produces more cell types along the myeloid lineage. The myeloid progenitor can differentiate into four other cell lines; erythrocytes – otherwise known as oxygen-carrying red blood cells. Immature erythrocytes can be identified by the presence of a nucleus, since they are similar in size and shape to mature erythrocytes – but a nucleus is ejected from the cell upon reaching full differentiation. (Ownby, 2002) Another differentiation event results in mast cells, whose release of histamine and heparin is responsible for many allergic reactions including anaphylaxis. Myeloid progenitors can also ...Download file to see next pagesRead More
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The topic of "Wet Lab. Cellular Replacement Therapy And Stem Cell Research." is quite popular among the assignments in high school. Still, this text opens a fresh perspective of seeing the issue. I’ll use the manner for my own essay.
Stem Cell Research
There are three main types of stem cells: embryonic, adult and induced pluripotent stem cells; of which, embryonic stem cells are found in early embryos and can have the potential of developing into any cell in the body. Adult stems are found in populations around the body after birth such as in the bone marrow and can develop into a limited range of cells, while induced pluripotent stem cells are grown in the laboratory and can be modified to be more specialized.
4 Pages(1000 words)Essay
Stem Cell Research
Interestingly, adult individuals retain some pluripotent cells, from which cells for replacement of damaged tissues can be derived. Thus, fibroblasts, muscles, red blood cells, or nerve cells can stem from a pluripotent stem cell upon initiation of specific physiologic conditions (National Institutes of Health, 2009).
3 Pages(750 words)Essay
Stem Cell Therapy
The division of stem cells yields to new cells that are potentially about to remain as a stem cell or a new cell type altogether. ( Segers, 2008)1 Stem cell therapy is a new innovation in the field of medicine. It is the process of introducing and supplementing new cells into damaged tissues to cure diseases, as well as injuries.
4 Pages(1000 words)Essay
Stem Cell Research
The pluripotent stem cells also referred as embryonic cells have the ability to differentiate into every cell of the body while the multipotent (adult) stem cells can only differentiate into multiple cells but not all cell lineages in the body. Research on stem cells spans a broad range of scientific and medical fields.
6 Pages(1500 words)Essay
Stem Cell Research
Currently, no research on human embryos can be supported with federal funds because of the controversial origins of these cells (Gerald D. Fischbach, 2004). The root of the argument lies around embryonic stem cells, which enable research that may support the development of medical treatments, but requires the destruction of an embryo to derive.
1 Pages(250 words)Essay
Stem Cell Research
The author discusses ethical and moral arguments of using embryonic stem cells. Arguments of groups or sectors opposing the use of embryonic stem cells revolve around the destruction of life because they consider the cell in the embryo as not just a simple cell but life itself or the beginning of a human being.
12 Pages(3000 words)Essay
Stem Cell Research - Stem cell research
Science and technology has developed so much that in the recent years scientists hope to use these cells to develop new tissues, treatments and potentially even organs for transplanting into a patient. First and foremost argument made by the scientific community is that human stem cell research is said to promise new life changing treatments and possible cures for many devastating diseases and injuries, such as Parkinson's disease, diabetes, heart disease, multiple sclerosis, burns and spinal cord injuries (Young 2-16).
4 Pages(1000 words)Essay
Stem Cell Research Legislation
strate the potential benefits of using stem cells to better the human condition, thus the Senate Labor and Human Resources Committee voted in favor of a bill designed to end President George H.W. Bush’s federal funding ban involving experiments allowing tissue transplantation
4 Pages(1000 words)Essay
Stem Cell Therapy
A stem cell is undifferentiated cell with the potential of differentiation into many types of organs and tissues (Conrad, 2012). Stem cell therapy operates on the basis of using undifferentiated cells to cure various diseases through
2 Pages(500 words)Essay
Benefits of stem cell research
The benefits of stem cell research far outweigh any potential disadvantages. The Benefits of Stem Cell Research. Stem cell research is one of the most controversial topics in contemporary medical and ethical debate. Stem cells are unspecialized cells which are capable of self-renewal and also of differentiation into specialized cells. These cells constitute an internal repair system, dividing limitlessly to replace damaged and worn-out cells as long as there is life.
5 Pages(1250 words)Essay
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