Summary to research paper on topic "Coronary Artery Disease"
Coronary Artery Disease or CAD is known as Coronary atherosclerotic heart disease has emerged as one of the leading causes of death in males as compared to females. Its progression constricts the extension of blood vessel leading to myocardial ischemia. Therefore, CAD results in…
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It is established that LDL or Low-density lipoproteins are chiefly atherogenic in nature. On the other hand high-density lipoproteins or HDLs are defensive lipids as they aid in LDL metabolism. On oxidation LDLs become tougher to metabolize and become cytotoxic leading to endothelial injury (Pollard, Let us write or edit the essay on your topic "Coronary Artery Disease" with a personal 20% discount.. Try it now 2009).
Chronic Endothelial injury Hypothesis- Endothelium protection and its repair is performed by glycosaminoglycan or GAGs, when GAGs become weak, atherosclerosis is instigated. The process is promoted due to exposure of endothelial cells and free-radical damage. As damage of endothelial lining is initiated the site promotes the permeability of plasma constituents especially the lipoproteins. Thus oxidized LDLs are capable of damaging the endothelial lining of the cells which results in the formation of plaque (Stephen, 2011).
When the endothelial cells are injured, the macrophages present in the blood move around from the blood circulation. The inner side of the artery forms a layer called layer of intima. Consequently, smooth muscles join intima along with connective tissue as well as lipids present inside as well as outside the cells to generate a plaque. This brings about union as well as accumulation of platelets, as well as release various growth regulating factors to amplify the procedure ensuing obstruction of the lumen of the artery, leading to thrombus establishment (Mottillo, 2010).
Mottillo, S., Filion, K. B., Genest, J., Joseph, L., Pilote, L., Poirier, P., Rinfret, S., Schiffrin, E. L., Eisenberg, M. J. (2010). The Metabolic Syndrome and Cardiovascular Risk: A Systematic Review and Meta-Analysis. J. Am. Coll. Cardiol, 56(14), 1113- 1132.
Stephen D. Wiviott, Marcus D. Flather, Michelle L. ODonoghue, Shinya Goto, Desmond J. Fitzgerald, Fernando Cura, Philip Aylward, Victor Guetta, Dariusz Dudek, Charles F. Contant, Dominick J. Angiolillo, Deepak L. Bhatt.
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Imbalance between demand and supply of oxygen to the muscles of heart can occur either due to decreased supply of oxygen to the heart muscle or due to increased oxygen demand, or both. The main cause for ischemia of the muscles of the heart is coronary artery disease and hence ischemic heart disease and coronary artery disease are often used synonymously.
Coronary heart disease has become one of the major causes of morbidity and mortality in the United States. With the increased rates of obesity and intake of processed and high cholesterol foods, this issue will likely continue to prevail in US society. In fact, coronary heart disease (CHD) or coronary artery disease (CAD) is said to affect about 14 million people in the United States alone (WebMD, p.
Smoking and Risk of Cardiac Disease. Cardiac disease is a major contributor for mortality and morbidity all over the world including the United States. One of the devastating consequences of heart disease is massive heart attack which has almost 100 percent mortality.
Most men acquire this disease in their 40s. Women generally acquire this disease later than in 40s. There can be many reasons for an individual to acquire the coronary artery disease. It may be gained because of bad genes. People who have a family history of heart attacks are more susceptible to the disease than others.
Coronary Artery Disease - Pathophysiology and Management Introduction Coronary heart disease is also commonly known as coronary artery disease. It is a condition in which plague builds inside the coronary arteries (Cohen & Hasselbring, 2007). These arteries supply oxygenated blood to the heart muscles.
Poor adherence to long term therapies compromises treatment effectiveness. As a result, the health of the population becomes a crucial issue from the perspective of health economics and quality of life. Any interventions directed to improve adherence should be affordable through secondary and primary interventions.
Coronary artery disease arises due to the buildup of plaques in the coronary arteries that lead to blockages. This is a state known as atherosclerosis (Brubaker, 2001). The arteries, which start out as elastic and smooth, become rigid and narrow. This restricts blood circulation to the heart (Brubaker, 2001).
Secondly, it outlines the compatibility of the Helen Fuld School of Nursing conceptual framework with the values of the coronary artery bypass surgery nursing. Thirdly, it explores the role of the nurse in detail during different phases of the surgery. Next, it reports the findings of an evidence-based study into the problem.
With rapid globalization, in many parts of the world, this is increasingly becoming the typical picture, and this disease is the most prevalent serious disease in elderly individuals of the developed Western nations. Therefore, in this context, it would be worthwhile to examine how this disease develops and how it manifests itself.
The idea of this research emerged from the author’s interest and fascination in how the social determinants of the disease in Merced County compared to California and the US. This research aims to evaluate and present a comparison of health outcomes related to the problem and the ongoing interventions or programs addressing this health condition in Merced County.
10 Pages(2500 words)Research Paper
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