383), authors set out to assess the safety and efficacy of using IV (intravenous) adenosine therapy for the emergency treatment of narrow complex tachycardias among patients with an initial diagnosis of presumptive supraventricular…
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The researchers collected demographics on the patients, including history, medications, vital signs, and ECG readings. This study revealed that out of the 41 patients included in this paper, 31 were correctly diagnosed with PSVT, one had sinus tachycardia, and nine had atrial fibrillation (Furlong, et.al., 1995, p. 383). In the 31 cases diagnosed with PSVT, 28 successfully had sinus rhythm after the administration of adenosine. This represents 90.3% of the population being studied (Furlong, et.al., 1995, p. 383). For patients who were converted to sinus rhythm, 16 of them were given a single dose of adenosine, nine of them were given one additional dose of adenosine, and three later required two additional doses of adenosine (Furlong, et.al., 1995, p. 383). None of the patients given adenosine reverted to PSVT after administration of adenosine; there was also no difference in length of asystolic pause or in the outcome which was seen between the actual PSVT and the AF cases receiving adenosine (Furlong, et.al., 1995, p. 383). No significant negative side effects were also seen in the patients given adenosine. This study concluded that adenosine can be an effective emergency treatment of narrow complex tachycardia, and it can also be safely administered without the necessary physician control. The authors recommended that this drug must be used as directed by the manufacturer and it is actually a valuable prehospital diagnostic adjunct in patients with atrial fibrillation (Furlong, et.al., 1995, p. 383).
In 2008, a paper by Ertan, et.al. (pp. 386-390) sought to assess the proarrhythmic potential of adenosine in terminating or treating supraventricular arrhythmias otherwise known as narrow complex tachycardia. This study was conducted as a retrospective paper reviewing the records of all patients who underwent adenosine treatment for the termination of supraventricular tachycardia. Patients who
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