Nobody downloaded yet

Human Growth Hormone Replacement Therapy and Aging - Essay Example

Comments (0) Cite this document
Synthesized in the anterior pituitary, the human growth hormone, also known as somatotropin, represents an important protein molecule, which promotes growth of many tissues in the body. It also influences several aspects of metabolism, such as increasing protein disposition in the bodies, utilization of fat as an energy source and reducing the use of carbohydrates as a main source of energy…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER98.4% of users find it useful
Human Growth Hormone Replacement Therapy and Aging
Read TextPreview

Extract of sample "Human Growth Hormone Replacement Therapy and Aging"

Download file to see previous pages in 2001. The scientists state that while the reduction of concentration of somatotropin during aging is documented, there were several problems with previous researches as they did not exclude the various gonadotropic hormones that were also reduced with old age. The study was performed on two groups, a young group, consisting of 8 men and 8 women, and an aging group consisting of 11 women and 10 men. All the subjects had similar body mass indexes and blood samples were taken from each of the test subjects every 10 minutes for 24 hours. The results from the research showed a marked decrease of 32-56% of growth hormone concentration, each according to its sex. 81% of the young group secreted the highest amount of growth hormone during the night period, while 62% of the aging group secreted most of the growth hormone during the day period. The researchers reached the conclusion that there is a decrease in secretion of growth hormone as age increases for both sexes. The reduced concentration of growth hormone was, in turn seen as a lack of growth hormone releasing hormone. (Russel-Aulet et al.)
Another research focuses on the problem of sarcopenia, which represents a syndrome that manifests itself as a decrease in skeletal muscle mass, as well as in muscle work output. As the natural process of aging involves degradation of skeletal proteins, sarcopenia is expected to appear in most of the elderly, but this condition can be aggravated by the lack of exercise, leading to more frequent physical injuries such as hip fractures. Aware of the low concentration of several hormones that affect protein anabolism in old age, amongst them the growth hormone, the scientists researched the coupled human growth hormone replacement therapy with resistance exercise, which is known to reduce the effects of sarcopenia, in people aged 60 and over. Although the research can be viewed as retrospective, as it presents the various experiments, as well as the results, performed by other researchers, a case-control trial was described that was performed by the authors of the paper. The study involved men from 62-75 years of age which were involved in a 16 week exercise program, consisting of modest to high-intensity training in the form of weight lifting exercises with a small repetition. It encompassed muscles from both the upper and lower extremities. One group was given a dose of 12-24 g/kg/d of growth hormone, while the other, control, group performed the same exercises, but was not given anything. The result from their research, as well as results from other researches, led the scientists to conclude that there is not much difference in muscle mass and strength between the control group and the group that received somatotropin. An increase in muscle mass was present, however, but not focused on the skeletal muscles. Furthermore, the scientists concluded that there were significant side effects from the use of somatotropin replacement therapy in aging people, further criticizing the use of somatotropin as a means to prevent sarcopenia. (Zachwieja, Yarasheski).
Sarcopenia is but one of the many physiological ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Human Growth Hormone Replacement Therapy and Aging Essay”, n.d.)
Human Growth Hormone Replacement Therapy and Aging Essay. Retrieved from
(Human Growth Hormone Replacement Therapy and Aging Essay)
Human Growth Hormone Replacement Therapy and Aging Essay.
“Human Growth Hormone Replacement Therapy and Aging Essay”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF Human Growth Hormone Replacement Therapy and Aging

Hormone Replacement Therapy

...?Running head: HORMONE REPLACEMENT THERAPY Hormone Replacement Therapy Insert Here Insert Affiliation Here Hormone Replacement Therapy Introduction: With advancements in medical science, it has now become possible to overcome any shortcomings, limitations or inconveniences concerning human health. Thanks to unconventional medical procedures, altering one’s innate characteristics, viz., gender, genetic makeup, physical appearances, etc., is not impossible anymore. One of the most significant advances of medical sciences is in the field of Hormonal...
5 Pages(1250 words)Essay

Growth Regulation Hormone

...reaches his adult height. [1,2,3,4] Background of Growth Hormone Secretion Growth Hormone is secreted in a pulsatile manner from the anterior pituitary gland. It is a peptide hormone consisting of 191 amino acid residues and contains 2disulphide bonds. The 20kda and 22kda isoforms are the important ones. There are 5 genes related to the GH molecule, of which GH-N, is the main gene and has its locus on 17q22-24.The other genes are GH-2 coding for placental GH, the CS1 and CS2 coding for human chorionic somatomamotropin, and the pseudogene CSP. GH exists in two forms in the circulation, in the free and active form while the other is the...
12 Pages(3000 words)Assignment

Aging-related growth hormone

... in both sexes, we cannot be yet certain that the same conclusions about the amplitude of growth hormone Releasing Hormone pulses can be applied to women. Growth hormone regulation in humans is sexually variable. Further studies are needed to test of the results are the same in women. Russell, Mary, Dimaraki, Eleni et al. "Aging-Related Growth Hormone (growth hormone) Decrease Is a Selective Hypothalamic growth hormone-Releasing Hormone Pulse Amplitude Mediated Phenomenon." Journal of Gerontology: medical sciences 56A (2001): M124-M129.... Review "Aging-Related Growth Hormone (growth hormone) Decrease Is a Selective...
3 Pages(750 words)Essay

Hormone Replacement Therapy and Breast Cancer

...Is There An Association Between Hormone Replacement Therapy And Breast Cancer Breast cancer is a hormone dependant malignancy. Carcinomabreast is the most frequent malignancy in women. The acquired mutation as a cause of malignancy has raised interests among investigators, and it has been postulated that gonadal hormones naturally play a significant role in proliferation of breast tissue in different phases of a woman's life, hence exogenous hormones would act as a promoter of this disease. In an attempt to find out the actual relationship of the hormones in development of breast cancer, there had been...
5 Pages(1250 words)Essay

Human Growth Hormone Replacement Therapy and Aging

...HGH Summary of theory Human growth hormone (HGH) has been in use for a relatively short amount of time, so there is still a lot of lively debate inpeer reviewed journals about its possible uses and misuses. One factor upon which HGH has a debated effect is age or longevity. On the one hand, when it is given to some clients, HGH can promote growth and fight some of the effects of aging; on the other hand, it is not as useful the older the person taking it is, and there are other limiting factors. “Growth hormone is clearly our master hormone because of its ability to affect all other...
4 Pages(1000 words)Essay

Growth hormone

...( Growth hormones can take effect in two- three months as how it is viewed by the people who use growth hormones but it varies depending on what effect a person wants to see. Usually, growth hormones are used to care for the growth disorders of children. And, this can be used to help adults stimulate their growth especially in cases like dwarfism (Low 38). Growth hormones are acquired through different methods and replacement therapies are widely accepted to be able to fight aging and manage weight...
2 Pages(500 words)Admission/Application Essay

Growth Hormone in Psychological Processes

...concentrations rise causing enlargement of the mammary glands. Also produced in the pituitary gland is the hormone vasopressin. Vasopressin also gets referred to as anti-diuretic hormone. This hormone encourages water retention by the kidneys. This hormone works in the kidney’s collecting ducts to stimulate reabsorption of water by the body. This action by the vasopressin hormone reduces the volume of urine. Anabolic steroids refer to man-made chemical substances almost similar to male sex hormones. Anabolic steroids get taken to build muscle, improve appearance or enhance performance. Growth hormones...
2 Pages(500 words)Research Paper

Hormone Replacement Therapy

...Hormone Replacement Therapy and cancer disease in Men and women Introduction Hormonal Replacement Therapy is the use ofhormones in medical treatment or treatment with hormone antagonists. The hormonal Replacement Therapy has been implied on treatment of cancer; for instance hormonal therapy for cancer and androgen deprivation therapy on prostate cancer, the treatment can also be done on aging for example hormone replacement therapy (menopause),...
2 Pages(500 words)Essay

Support for hormone replacement therapy

...Hormone Replacement Therapy Hormone Replacement Therapy Many benefits for which hormone replacement therapy is applauded as a good treatment for hormone deficiency exist. Despite these benefits, hormone replacement therapy has some limitations. There are also reasons why one can support the use of hormone replacement therapy and why one can recommend alternative treatments for hormone deficiency. Benefits of hormone replacement therapyHormone replacement therapy can help treat vasomotor symptoms. An example of a vasomotor symptom that hormone replacement therapy can treat is hot flushes that are associated with a drop in the levels of estrogen. Hormone replacement therapy is beneficial in the treatment of urogenital atrophy... by...
3 Pages(750 words)Assignment

Hormone replacement therapy

...Hormone replacement therapyHormone replacement therapy (HRT) was once regularly used to control symptoms of menopause and safeguard long-term health. Specifically, HRT involves administering medications which are rich in female hormones to substitute the natural ones whose production no longer takes place in the body after menopause. HRT is principally used as normal cure in women suffering from hot flashes, night sweating, and itchiness of the female reproductive system especially during intercourse in their menopause. HRT was also believed to have the permanent benefits of reducing the risks to heart disease and dementia. The benefits of Hormone Therapy The advantages of hormone therapy are dictated, in part, by the mode... uterus has...
4 Pages(1000 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Essay on topic Human Growth Hormone Replacement Therapy and Aging for FREE!

Contact Us