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Effective Ways to Cure Malaria - Book Report/Review Example

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This essay analyzes that Malaria is considered to be one of the major health problems in the Third World countries. Malarial endemic conditions vary from country to country based on the malaria epidemiology and the level of the control program implementation in those countries…
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Effective Ways to Cure Malaria
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Download file to see previous pages Although P.vivax is the widest spread form of malaria infection in the world, Plasmodium falciparum causes the most severe disease and responsible for most deaths and serious morbidity (Gbotosho et al., 2011). Malaria is also regarded as a social and behavioral problem, and that contributes to the perception and treatment of the disease. Malaria has become one of the deadly diseases in the world. The first line drug initially used for the treatment of malaria was Chloroquine. Plasmodium falciparum became resistant to the chloroquine drug. Hence, the search for the new potential drug for the treatment for malaria was started and drugs such as Sulfaxonine – pyrimethamine, Mefloquine, Halofantrine, 4- aminoquinoline, amodiaquine, hydroxyl chloroquine and artemisinin-based combination therapies were tried for the treatment of malaria. The Artemisinin-based combination therapies (ACTS) are found to be more effective than all the other drugs. The extensive studies for the treatment of malaria have proved that ACTs could be the optimal solution for this disease.
The history of drugs used for the treatment of malaria goes back to hundreds of years. In 1820, quinine, an alkaloid, was identified as an important therapeutic agent for malaria. However, quinine has a very short shelf life and hence, chloroquine was identified and used for the treatment of malaria. Chloroquine has a prolonged half-life of 33 days and is active against asexual stages of all human species, except for strains of P.falciparum (Rukaria-Kaumbutho, Ojwang, & Oyieke, 1996). The low toxicity, low cost and importantly effectiveness to treat malaria are the essential factors, which are focused when choosing the treatment for malaria. Many malarial programs were planned and implemented but there are certain barriers for the complete success of the program. The major barrier to the treatment of malaria is the lack of proper attention to the right drugs.  ...Download file to see next pagesRead More
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