Nobody downloaded yet

A Metabolic Disorder Posing Serious Threat Worldwide - Literature review Example

Comments (0) Cite this document
Summary
This paper aims to review existing clinical studies and literature involving the use of pregabalin and gabapentin in the treatment of diabetic neuropathy. This paper seeks to determine if pregabalin is a better choice of treatment over gabapentin in the management of diabetic neuropathy…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER93.9% of users find it useful
A Metabolic Disorder Posing Serious Threat Worldwide
Read TextPreview

Extract of sample "A Metabolic Disorder Posing Serious Threat Worldwide"

Download file to see previous pages Healthcare practitioners acknowledge neuropathy as among the most common and costly complications of both Type I and Type II diabetes.47 Diabetic neuropathy, which is characterized by progressive loss of nerve fibre integrity and function, may be grouped under two general types according to the anatomical distribution of damage: diffused or focal neuropathy.8 Diffused neuropathy, the most common, chronic and progressive type is represented by Diabetic Polyneuropathy (DNP) and Diabetic Autonomic Neuropathy (DAN).8 Focal forms of diabetic neuropathy include mononeuropathy, mononeuropathy complex, plexopathy, radiculopathy, and carina neuropathy. Although it covers a variety of forms, diabetic neuropathy in general causes continuous burning and painful sensation, ulcerations, restricted mobility and is associated with abnormal sensory functions such as allodynia (i.e. perception of pain from the non-painful stimulus).23,35,47 In fact, according to Rice et al (2001) diabetic neuropathy is the number one cause of non-traumatic leg amputations.35 The anticonvulsant, anti-nociceptive, and anxiolytic drug, gabapentin, originally developed for the treatment of epilepsy, is now a widely used pharmacological agent for the management of painful diabetic neuropathy.1,30 Gabapentin is a structural derivative of the neurotransmitter gamma-aminobutyric acid (GABA).38 Studies have illustrated that gabapentin binds to alpha-2-delta subunits of voltage-dependent calcium ion channels, subsequently blocking central sensitization and occurrence of hyperalgesia. ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
  • CHICAGO
(A Metabolic Disorder Posing Serious Threat Worldwide Literature review, n.d.)
A Metabolic Disorder Posing Serious Threat Worldwide Literature review. Retrieved from https://studentshare.org/management/1737079-is-pregabalin-a-better-choice-for-patients-with-diabetic-neuropathy-than-gabapentn
(A Metabolic Disorder Posing Serious Threat Worldwide Literature Review)
A Metabolic Disorder Posing Serious Threat Worldwide Literature Review. https://studentshare.org/management/1737079-is-pregabalin-a-better-choice-for-patients-with-diabetic-neuropathy-than-gabapentn.
“A Metabolic Disorder Posing Serious Threat Worldwide Literature Review”, n.d. https://studentshare.org/management/1737079-is-pregabalin-a-better-choice-for-patients-with-diabetic-neuropathy-than-gabapentn.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document

CHECK THESE SAMPLES OF A Metabolic Disorder Posing Serious Threat Worldwide

Gout as a Metabolic Disorder

...? GOUT Word Count 2766 INTRODUCTION Gout is a metabolic disorder ically represented as acute inflammatory monarthritis (Rott & Agudelo, 2003); that is known to be initiated by the crystallization of uric acid (UA) within the joints. Uric acid is the end product of metabolism of purine. When urates in the blood reach the physiological saturation levels, they crystallize to form monosodium urate (MSU) and gradually accumulate in tissues. This leads to development of asymptomatic hyperuricemia which results into gout (Luk & Simkin, 2005). The clinical manifestations of gout include acute gouty arthritis, deposition of MSU crystals in soft tissues leading to formation of ‘tophi’, urate...
11 Pages(2750 words)Research Paper

Hilton Worldwide

...? SHAN LEIM005 AS2 Table of Content Introduction 3 Aspects of development 4 Global market positioning 5 Market segmentation 6 Business networking andrelation 7 Strategies for customer satisfaction 9 Conclusion 11 Reference 12 Bibliography 13 Introduction Hilton Worldwide is one of the largest and prestigious hospitality companies in the world which is well popular across the world. This company owned by a big private equity firm, Blackstone group. Hilton worldwide owns and efficiently manages a portfolio of 10 popular and big brands in this hospitality industry. The company formerly named as Hilton Hotels Corporation. It is an US based company. The company has business operation in 88 countries through...
10 Pages(2500 words)Assignment

Metabolic Syndrome

...?Metabolic syndrome History Metabolic syndrome is a complex of conditions which prove to be a risk factor for the development of Cardiovascular Diseases. Metabolic syndrome can be traced back to the findings of a renowned physician named Jean Vague. He found out that obesity was directly related to the metabolic disorders of the body. But these metabolic disorders were not related to the abnormalities of the cardiovascular system at that time. Gerald Phillips later on found out that the aspects of ageing, obesity, and diabetes were directly related to heart diseases. It was then in 1988 that Reaven found out a connection...
6 Pages(1500 words)Essay

Metabolic Syndrom

...the functioning of the heart, quitting smoking, losing weight and maintaining a commendable, physical fitness (Mellissa 2010). A doctor may also prescribe drugs that control the risk factors like high triglycerides, high blood pressure, high blood sugar and low HDL cholesterol. Further drugs can be used to reduce blood clotting in the arteries. Treatment Goals The chief goal of treating metabolic syndrome is to lower the danger of heart problems. Treatment is focused initially on managing diabetes, lowering blood pressure and LDL cholesterol in the blood (Mellissa 2010). The next goal of treatment process is to avoid the onset of type-two diabetes because it can cause serious complications like vision...
5 Pages(1250 words)Research Paper

Are plastic bags posing a great threat to our environmentsolutions to plastic bags recycling

...by recycling? B. Secondary Research Questions How are plastic bays a threat to the environment? How serious is the environmental threat posed by plastic bags? Can recycling minimize the environmental threat posed by plastic bags? What other measures can be taken to minimize the environmental threat posed by garbage bags? III. Statement of the Problem Plastic bags are cheap to produce and convenient for consumers to use as a result they are reportedly overused and a major source of litter globally (Ready, 2011). As a “non-biodegradable” product, plastic bags as a source of litter pose a...
17 Pages(4250 words)Dissertation

Metabolic Syndrome

...factor (Byrne, 2011). The management and treatment of the metabolic syndrome is not precise to the syndrome; however, it involves: (1) Managing of the underlying factors for diabetes and CVD. (2) The management of any developed disorders such as kidney disease, hypertension, diabetes, and heart diseases. (3) Evaluation and treatment of CVD impacts without repute to whether a patient meets the standards for diagnosis of the MetS (Wang, 2011). The most key objective of managing and treating MetS is to reduce an individual’s risk of diabetes and heart disease (Bagchi, 2012). In most cases, the healthcare providers recommend lifestyle changes to assist in lessening blood sugar, blood pressure, and LDL...
4 Pages(1000 words)Assignment

Posing a problematic question

...Posing a Problematic Question A problematic question is a debatable doubt about something that can be argued in differentways. The most probable problematic question in this picture is; is this area good enough for people to live in? A possible habitable environment should be clean, on a leveled ground and free of rocks, on the contrary, in the picture; the area is steep with many rocks that could be a very habitable area for snakes. It is not strange to find a snake in such a place; we know that snakes hide in rocky places. Unleveled grounds such as the one in the picture do not provide a suitable environment for humans to live in. Putting up a home requires flat and leveled ground. According to the picture, the area in...
1 Pages(250 words)Essay

Metabolic Changes

...Metabolic Changes Physical exercises, whether high-intensity or low intensity, affect the metabolic system of an individual. In line with this, metabolic changes take place in order to accommodate the demands of the body during exercises. While doing this, there are metabolic requirements that a body should have in order to ensure the achievement of effective results. This expose is an elucidation of all the changes that take place in the body’s metabolism processes during physical exercises. First, the expose elucidates on the cardiovascular and respiratory changes that take place in the body during physical exercises in order to accommodate the needs...
3 Pages(750 words)Essay

Metabolic Syndrome

...Metabolic Syndrome due: Concept map Genetic factors, poor diet, inadequate exercise Adipose cell enlargement & infiltration of macrophages into adipose tissue Release of proinflammatory cytokines Adipose tissue dysfunction & insulin resistance Inadequate insulin production & beta cell dysfunction Obesity related insulin resistance Increase in free fatty acid levels & changes in insulin distribution Abnormalities in insulin secretion, insulin signaling, improved glucose disposal, proinflammatory cytokines The symptoms presented by the patient reveal that he is suffering from Metabolic Syndrome. Diagnosis of this condition was based on his laboratory exam results...
2 Pages(500 words)Assignment

Metabolic Disorders Case Studies

...[Teacher’s Metabolic Disorders Type 2 diabetes is a metabolic disorder that commonly develops after forty years of age on the background of different etiological factors. Studies have suggested that the etiology of the disease may have some genetic predisposition. There are also other etiological factors that have been found to act independently or in the background of genetic factors to cause Type II diabetes. These etiological factors include any activities that involve a “diabetogenic lifestyle” such as the consumption of a high calorie diet, obesity and a sedentary lifestyle (Vijan, 1). Other risk factors to developing type II diabetes include age, race, and history...
2 Pages(500 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Literature review on topic A Metabolic Disorder Posing Serious Threat Worldwide for FREE!

Contact Us