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Bovine Tuberculosis, Anthelmintic Treatment, Worms and their Effect on the Immune Response to other Pathogens - Assignment Example

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The author examines Bovine tuberculosis (BTB) disease caused by Mycobacterium bovis., and Helminths treatment,  worms and their effect on the immune response to other Pathogens and effect on any future TB vaccine. The author also identifies whether anthelmintic treatment facilitate the spread of TB …
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Download file to see previous pages If a dairy farmer suspects that there are positive TB infection cases in his or her herd, they can conduct a Single intra-dermal Comparative Cervical Tuberculin (SICCT) test to diagnose suspected cases. The SICCT test measures a delayed mode hypersensitivity response to the tuberculin antigen, Purified Protein Derivative (PPD) and is dependent on functional antigen-specific. However, use of SICCT test does not produce confidence levels required to ascertain the success of the tests. The diagnostic sensitivity of the SICCT test is estimated to be between 52-100% with a median value of 80% using the standard interpretation of the test. Factors attributed to the inaccuracy, and the poor sensitivity of the test include among many; the effect of concurrent infection with pathogens that may suppress the immune response to Mycobacterium bovis (Claridge et al., 2012).
Therefore, prior to testing, it is important for a farmer to treat his herd with flukicidal drugs. It was established that flukicidal drugs increase the detection rate of BTB, which leads to a short-term to an apparent surge in the incidence, though, in the long-term, it may result in control of the disease. If positive skin tests reveal high cases that were displayed during the SICCT tests, then the farmer needs to administer flukicidal drugs to increase the reliability of the SICCT tests. After the initial testing, the farmer also needs to conduct the test again after sixty (60) days to ascertain total elimination of infected cattle from the healthy ones. If the cattle test negative after the 60-day window, then the herd can be considered TB free (Claridge et al., 2012).
The dairy farmer should also be on the lookout for a trematode parasite that affects livestock known as Fasciola hepatica. ...Download file to see next pagesRead More
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