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Polycystic Kidney Disease - Research Paper Example

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Polycystic kidney disease is a genetic disorder that occurs in two main ways: as autosomal dominant polycystic kidney disease and as autosomal recessive polycystic kidney disease (NIDDK ). In both cases, the disease causes multiple cysts to grow on the kidneys, which can cause further health complications involving other bodily systems (NIDDK)…
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Download file to see previous pages Cysts may also form in other organs (Mayo). Although the disease can be very serious, it is possible for a person to have the disease for years without being aware of it (Mayo). Since the disease is genetic and runs in families, family members might be more likely to watch for symptoms and identify the cause of the symptoms than they would be for a disease that was not genetic in nature. A third form of the disease, acquired cystic kidney disease, has no genetic implication and is usually associated with kidney failure (NKF). The symptoms of polycystic kidney disease include high blood pressure, pain in the back or side, headache, swollen stomach area, bloody urine, frequent urination, kidney stones, kidney failure, urinary tract infections, and kidney infections (Mayo). While these symptoms are generally evident in both forms of the disease, there are some characteristics of the autosomal dominant form of polycystic kidney disease that are different from the autosomal recessive form of the disease. Autosomal dominant polycystic kidney disease is a relatively common hereditary disease, and it eventually causes kidney failure in about half of the people who have it (Masoumi et al.). The symptoms of this form of the disease are most likely to surface at around thirty to forty years of age (Mayo). About ninety percent of polycystic kidney disease cases are of the autosomal dominant form (Mayo). A child can inherit this disorder even if only one parent has the disease, and a child with one parent who carries the disease has a fifty percent chance of having the disease (Mayo). On the other hand, autosomal recessive polycystic kidney disease is relatively rare (NIDDK). Unlike the disease’s autosomal dominant form, symptoms of the recessive form often surface not long after a child is born (Mayo). Less frequently, they don’t show up until childhood or adolescence (Mayo). Unfortunately, the symptoms can even be severe enough to cause death within hours of the infant’s birth (NIDDK). The only way a child can have this form of the disease is for both parents to be the carriers of abnormal genes (Mayo). When both parents carry this abnormal gene, each child they have has a twenty-five percent chance of having the disease (Mayo). The first symptom reported by most individuals with autosomal dominant polycystic kidney disease is back pain, which varies in intensity from person to person (NIDDK). Other symptoms of autosomal dominant polycystic kidney disease include urinary tract infections, bloody urine, cysts in the liver and pancreas, high blood pressure, kidney stones, and aneurysms in the brain (NIDDK). Another problem associated with this form of the disease is diverticulosis, a problem with the structure of the colon walls in which they become weak (NIDDK). The symptoms of autosomal recessive polycystic kidney disease include many of the same for the autosomal dominant form of the disease. Elevated blood pressure, urinary tract infections and increased urinary frequency are all common (NIDDK). Due to liver and spleen involvement, varicose veins and hemorrhoids are also likely in this form of the disease (NIDDK). Children with autosomal recessive polycystic kidney disease are smaller than other children due to the impaired functioning of their kidneys (NIDDK). These children will also have lower blood cell counts than the normal range (NIDDK). Another ...Download file to see next pagesRead More
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