Abnormalities of Schizophrenia - Research Paper Example

Statistical estimates of the genetic epidemiology of schizophrenia confirm that a high degree of heritability factor is fundamental to the psychological disorder of schizophrenia. A review of the scholarly literature on the question of schizophrenia in relation to heritability also supports the claim that heritability is a crucial factor in schizophrenia. However, it is essential to realize that the estimates of heritability show a high level of discrepancy as a result of the complexity in taking apart the effects of genetics and the environment on schizophrenia.

Therefore, an investigation into the psychological disorder of schizophrenia as having a high degree of heritability is an essential contribution to the study of genetics and neurobiology. Although schizophrenia has been the most studied of all psychiatric disorders in relation to heritability, this research focuses on the abnormalities of the neuroanatomical pathways and neurophysiological function believed to cause schizophrenia and this study undertakes a reflective analysis of the available scholarly literature on the topic.

An Annotated Bibliography Costello, Charles G. (Ed). (1993). Symptoms of Schizophrenia. New York: John Wiley and Sons. One of the most resources on the study of the abnormalities of the neuroanatomical pathways and neurophysiological function of schizophrenia. This significant writing brings about the link between basic science and clinical insights through the exploration of schizophrenia research and it makes a vital contribution to the understanding of various abnormalities of Schizophrenia in connection with heritability.

Significantly, “this new book brings together many of the most productive and admired investigators in those areas of research, individuals who have contributed most to contemporary developmental models of schizophrenia. Each of the chapters provides a state-of-the-art overview of the authors’ area of expertise, including directions for future.” (Keshavan, Kennedy, and Murray, 2004, p. xvii). Therefore, this book is an essential resource for investigation on abnormalities of schizophrenia and the role of heritability.

Turetsky, Bruce I., Moberg, Paul J., Mozley, Lyn Harper., Moelter, Stephen T., and Agrin, Rachel N. (2002 ). “Memory-Delineated Subtypes of Schizophrenia: Relationship to Clinical, Neuroanatomical, and Neurophysiological Measures.” American Psychological Association, Inc. Neuropsychology. 16, (4). pp. 481–490. In this article, Turetsky, Moberg, Mozley, Moelter, and Agrin (2002) examine memory performance in patients with schizophrenia in order to identify subgroups conforming to cortical and sub-cortical dementias and to determine whether these subgroups differed on clinical, neuroanatomical, and neurophysiological measures.

It is one of the essential articles on neuroanatomical pathways and neurophysiological function of schizophrenia. In this study, “the authors conclude that categorizing patients on the basis of memory deficits may yield