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The Molecular Forms of Cholinesterase - Term Paper Example

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In the essay “The Molecular Forms of Cholinesterase” the author analyzes a chemical compound that comes under few organophosphorus insecticides that had been developed and used during the 1950s. This pesticide is very commonly used in agriculture…
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The Molecular Forms of Cholinesterase
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Download file to see previous pages However, although it is used heavily it is very harmful and its consequences cannot be ignored at any cost. The compound, malathion, causes damage to the various parts of the body and thus it is important to consider the amount of malathion used and for the what purpose.
Malathion is an organophosphate parasympathomimetic and following a chemical reaction, it irreversibly binds with cholinesterase. Its International Union of Pure and Applied Chemistry (IUPAC) name is O, O-dimethyl dithiophosphate of diethyl.
Malathion is the first member of the family of organophosphorus compounds and its insecticidal properties are quite a few while having low mammalian toxicity. However, through a study, it was found that the children having high levels of organophosphate pesticide metabolites in their urine very often suffer from attention deficit hyperactivity disorder (ADHD) (Maugh).
Too much malathion in a body is harmful. The muscarinic symptoms resulting from high malathion exposure is that the affected person perspires too much, his pupils constrict and lacrimation takes place. Salivation, cramps in the abdomen, diarrhea, nausea, vomiting, chest tightness and difficulty in breathing are among the other signs. Nicotinic symptoms that may arise are muscle weakness, cramped or twitched muscles, ataxia, and paralysis.
The synthesis of malathion involves a reaction of the acid with diethyl maleate. The reaction takes in a single step. P4S10 is reacted with methanol resulting in the synthesis of acid. This is then added to diethylmaleate and there is no such need to isolate it from the reaction mixture. The chemical equation that is formed by this reaction in words and formula. ...Download file to see next pagesRead More
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