Nobody downloaded yet

Drug profile - Essay Example

Comments (0) Cite this document
SALBUTAMOL SULFATE Chemical Name: a1-[(tert-butylamino)methyl] -4-hydroxy-m-xylene-a, a'-diolsulfate (2:1)(salt) Generic Name: Salbutamol Sulfate Trade Names: As listed by Australia’s Department of Health and Ageing, Salbutamol sulfate is available in the market as Ventolinrotacaps or Ventolin syrup…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER91.8% of users find it useful
Drug profile
Read TextPreview

Extract of sample
"Drug profile"

Download file to see previous pages Indications: - bronchial asthma (RACGP, 2006; Lullman et al., 2000), - bronchitis (RACGP, 2006) - exercise-related dyspnea (RACGP, 2006) - other breathing problems (RACGP, 2006). - pre-term labour (Morgan et al., 1987). According to the Medical Reference Manual by Adult Retrieval Victoria (2011), Salbutamol (5-10 mg or 8 puffs 10-15 minutely) is one of the standard therapies for refractory asthma. Continuous nebulised Salbutamol is also used for maximum pre-intubation therapy. As well, the Queensland Ambulance Service (2011) lists approved emergency indications as bronchospasm and suspected hyperkalaemia with QRS widening and/or AV dissociation (Medical Director’s Office 2011 p. 69) for adult and paediatric administration (p. 70). Contraindications against paramedic use of salbutamol have been reported to include potential synergism with other sympathomimietics. It should also be used with caution in patients with diabetes, hyperthyroidism, and cerebrovascular disease (Albuterol 1999, p. 1). List of drug-drug interactions with Salbutamol (Albuterol 2011) Medicine name Strength Atomotexine – may cause CVS effects such as tachycardia and hypertension case reports Digitalis – hypokalemia induced by salbutamol may cause cardiac glycoside toxicity Mechanism already elucidated Diuretics – hypokalemia Steroids – hyperglycemia or hypokalemia Sympathomimetics – additive effects Theophylline – additive effects Xanthine derivatives –hypokalemia Bendrofluazide – augments hypokalemia, cardiac effects, arrhythmia Signal Transduction Mechanisms for ?2 Receptors Figure 1.The messenger system starting with the activation of receptor, which stimulates the G-protein to dissociate into its subunits. The ?-subunit then activates the enzyme converting ATP to cAMP. Figure from Guyton, A. C. and Hall, J. E. 2006. Textbook of Medical Physiology. Philadelphia: Elsevier. Salbutamol is an agonist of the beta 2 adrenergic receptors found on the smooth muscle lining airways of the lungs (Lullman, 2000). The intracellular components of the receptor are associated with G protein. In turn, G protein has three sub units (alpha sub unit, plus tightly associated beta, and gamma sub units). Upon binding of salbutamol to ?2 receptor, the latter activates the G protein, causing GDP (guanosine 5'-diphosphate) associated with the G protein to be phosphorylated to GTP (guanosine 5'- triphosphate), which initiates detachment of alpha subunit. The alpha subunit binds with adenylyl cyclase, which catalyses the conversion of ATP to cAMP (adenosine 5'-triphosphate to adenosine 3',5'-monophosphate) (Guyton and Hall, 2006). cAMP then inhibits myosin light chain kinase which is responsible for the contraction and hence constriction of bronchial smooth muscle (Klabunde, 2008). The inhibition of myosin light chain kinase promotes the physical relaxation and hence dilation of the smooth muscle lining of the affected airways which improves the potential for improved respiration which is key to addressing several pulmonary disorders Evidence of Clinical Effectiveness Despite being the most used ?2-agonist, research on the clinical effectiveness of Salbutamol had contradicting results. In a randomized control trial on salbutamol against preterm labor, 100 women, ages 17-32 years old and between 20-37 weeks pregnant, were recruited. ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Drug profile Essay Example | Topics and Well Written Essays - 2000 words”, n.d.)
Retrieved from
(Drug Profile Essay Example | Topics and Well Written Essays - 2000 Words)
“Drug Profile Essay Example | Topics and Well Written Essays - 2000 Words”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document
Drug profile of pharmacology ( Naloxone )
Opioids are the morphine like synthetic drugs that produce the same effect as that of morphine for pain relief, respiratory depression, constipation and sedation. Opioids antagonists block the (µ , ? and ?) opioid receptors. (Flomenbaum et al. 2006). Opioid antagonists, when administered before treatment, block the opioid agonists by preventing their action.
8 Pages(2000 words)Essay
Naloxone's Drug Profile
The bioavailability is low due the significant first-pass hepatic metabolism (O’Malley-Dafner 7; Davies 722-3). Part Two Orally administered, Naloxone undergoes a wide metabolism in normal subjects. It is minimally absorbed when given orally as it is quickly destroyed in the GI tract.
7 Pages(1750 words)Essay
Woman Drug Users
The study addresses the prevalent use of illegal drugs, particularly among women, in various countries including Bucharest, Muntenia, Transylvania, and Moldova (Bucur, 2010, p. 102). In identifying the characteristics of female drug dealers and consumers, the study also considers the underlying motivation for using illegal drugs and the existing government policies addressing the issue, which also include the impact of such policies on welfare and rehabilitation of drug users.
4 Pages(1000 words)Essay
Drug Profile Paper
Continuous abuse of these substances always leads to negative consequences which can even lead to loss of lives and reputation in social set up. These abused substances fall under different categories due to the nature of their origin and how they affect humans when abused and are discussed below.
6 Pages(1500 words)Essay
Pharmacology Drug Profile
Other names: Anestacon, Esracaine, Gravocain, Leostesin, Lidoderm, Maricaine, Cappicaine. (Upfal 2006). Molecular weight : 234.33728. (Upfal 2006). Molecular formula: C14H22N2O. It is a generic and prescribed drug under Schedule S.3, 4 in Australia. Figure1: Chemical structure of Lignocaine.
11 Pages(2750 words)Essay
Drug Profile activities for Module 2
46). Overall indication: the clinical characteristics were noted prior and after administering three nebulizations at an interval of 20 minutes in exactly an hour of presentation viz-respiratory rate, heart rate, oxygen saturation in room air SPO2, PEFR, serum K+ levels
2 Pages(500 words)Research Paper
Response paper
He describes how people engage themselves to work and false businesses just to kill boredom or make money. Individuals make work important only as means to these ends. He suggests that negative attitude towards work is destruction to creativity in its making
1 Pages(250 words)Essay
Pharmacology (Drug Profile Midazolam)
(Reves et al. 1985). 1. The chemical name of the drug is 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine. 2. The approved indications of the drug a) Intravenous administration along with an opoid is done for sedation and for the induction of the general anaesthesia and for ventilation of the sedated patients.
11 Pages(2750 words)Essay
Drug Profile Chart
Include a reference page citing your resources, and include sources other than websites. Also experience wakefulness, talkativeness, increased heart rate and blood pressure, dilation of the pupils of the eyes, a rise in body temperature, constriction of blood vessels, and a reduction of appetite.
2 Pages(500 words)Essay
Organizational profile
citizens by taking initiative on its own to collectively create, maintain, and better its strengths for protecting its people belonging to all communities from different natural or man-made unforeseen calamities and acts of terrorism. FEMA coordinates government’s role of
2 Pages(500 words)Essay
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Let us find you another Essay on topic Drug profile for FREE!
logo footer
Contact us:
Contact Us Now
FREE Mobile Apps:
  • StudentShare App Store
  • StudentShare Google play
  • About StudentShare
  • Testimonials
  • FAQ
  • Blog
  • Free Essays
  • New Essays
  • Essays
  • Miscellaneous
  • The Newest Essay Topics
  • Index samples by all dates
Join us:
Contact Us