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Drug Patch Design - Research Paper Example

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Many of the agencies astronauts suffer from the problem of motion sickness which prevents them from working efficiently while in space and leads to loss of extremely valuable…
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Drug Patch Design
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The patch I shall design would work for at least 60hours at a stretch and would work on all types of skin. Here I shall examine the rates of design patch on fast skin and slow skin to help me come up with an efficient design for all. The parameters that I shall be controlling and altering are membrane thickness L, diffusivity D, and the concentration of Scopolamine in the reservoir Cp. The second layer acts as the reservoir in which the drug is added in a predetermined concentration. It is from this layer that the drug would diffuse into the layer layers and ultimately into he skin.

The final layer which would stay in touch with the skin of the wearer would be membranous and permeable such the drug can easily diffuse out of the patch and into the skin. When the patch is put on, the drug slowly diffuses out of its layer into the next layer and travels right down to the skin layer and diffuses through it. It crosses the body barriers and enters the blood stream continuously thereby ensuring that the astronauts would not suffer from motion sickness as long as they wear a working patch.

I plotted the graph of concentration versus time in the body to understand which concentration lasted longer in the body since my aim was at least 60 hours.From these plots I selected the best effective concentration. All this was studied for maximum diffusivity (D2) and fast skin (l2). The main purpose is to design a perfect patch which can be worn by all astronauts and which would work efficiently for a long stretch of time. If the time it is required to work for is less than or exceeds its requirement the patch would not be usable.

On the other hand another rimportanat factor would be the concentration since a slightly higher concentration may have negative side effects on the astronauts. The several layered patch would last for a long time thereby supplying the drug to astronauts in order to curb motion sickness passed simulation tests and could now be used

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