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The research question that directed this study was: What is the effect of Oxygenation of Red Blood Cells (RBC) among Thalassemic? The aim…
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Download file to see previous pages The unstable alpha chains develop insoluble inclusions that occur within the bone marrow thus reducing the chances of development and survival of red blood cells. Therefore, the results of this research would assist to determine whether or not patients suffering from beta-Thalassemia could be assisted health wise by oxygenating their Red Blood Cells.
Patients of one Thalassemic Unit from the selected hospital of the study were engaged in this research. The patients were persons attending regular transfusion units; all the patients involved in the study were persons attending Chelation therapies. However, those that were experiencing certain challenges associated with respiratory of cardiac problems were not involved in the study. The consent of all the patients involved in the study was sought before engaging them in the experiment.
The data gathered was analyzed statistically. The Wilcoxon’s test was applied to analyze the collected data. This was specifically performed on paired data coupled with the application of Repeated Measures of Analysis of Covariance by using the SPSS 13.0 version. The analysis also involved the evaluation of Normality of Distribution for the continuous variables. Appropriate performance of linear regression was also involved in the data analysis process.
The results findings of the study indicated that tissue oxygen saturation increased significantly after the Red Blood Cells transfusion as compared to the baseline, which was at 88% while against 90%. The consumption of oxygen among patients with beta Thalassemic conditions did not exhibit any significant change after the transfusion. The repeated measures of ANCOVA also indicated that increasing hemoglobin through transfusion of Red Blood Cells facilitates the increase of saturated tissue oxygen. These findings are related to the conclusion ...Download file to see next pagesRead More
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