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Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children - Assignment Example

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The disease also affects the muscle lining the nerves and the blood. The disease interferes with digestion and absorption due to…
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Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children
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"Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children"

Download file to see previous pages Conducted to an average mean age of six, the children underwent gastrointestinal, developmental tests and neurological testing. The results show that all the children had gastrointestinal disease and poor development. The poor development is associated with the change of environment from their homes to the pediatric facility (A J Walkfield, 1998).
The method of testing includes the clinical investigation, laboratory investigation and histology. Developmental testing is conducted with the help of the parents. Ileocolonoscopy is then conducted after bowel preparation. Biopsy samples of the mucosa are then taken for testing from the terminal ileum. Urine is also tested to measure the amount of urinary methylmalonic acid. Magnetic imaging resonance is conducted to check the cerebral response. Stem auditory and sensory together with lumbar puncture is also done.
None of the 12 children showed neurological abnormalities according to the clinical tests. Child number eight-showed slow development because of an earlier operation on her aorta. Eight of the children showed poor development due to infection of measles, mumps or rubella vaccination. All the children tested negative for antiendomyseal test. Eight children were reported to have mucosal and rectal abnormalities. Terminal lymphoid hyperplasia was also reported in nine children. Parasites and organisms were not present in the intestines of the 12 children. The goblet cells were not also depleted.
The developmental regression results from of loss of coordination in the bladder or bowel function. The increased permeability into the intestinal walls is as a result of deficiency of the phenyl-sulphur transferase enzyme. Strains of measles vaccine have been traced to children suffering from autoimmune hepatitis hence playing a major role in the developmental regression. Vitamin B12 was deficient in the children since there was an increase in the methylmalonic acid concentrations. Vitamin B12 ...Download file to see next pagesRead More
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