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Biology on Diabetes - Essay Example

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The focus of the study “Biology Essay on Diabetes” states the effects of genetics, oxidative stress and atherosclerosis to the proneness of diabetics to retinopathy. The damages from retinal endothelium are lessened by the action of the component of turmeric known as curcumin. …
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Biology Essay on Diabetes
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Download file to see previous pages According to Hsieh et. al. (2005 quoted in Morhan et. al. n.d., p. 15), various organs like the kidney and liver showed some lowered levels of mtDNA 8-OHdG when the rats were treated with rice bran oil. It showed that the oil may have certain properties that would be helpful to diabetics. Another study coming from Molnar et al. (n.d. as cited in Morhan et. al. n.d., p. 15) suggested that circulatory system illness and diabetes can be caused by angiotensin-converting enzyme gene insertion and deletion polymorphism. Those who have allele D may experience a heightened oxidative stress. It then leads to the injury of endothelium. Oxidative stress is then detected by the presence of albuminuria. Albuminaria may have some linkage with type 2 diabetes as what was investigated by Molnar et al. (n.d. cited in Morhan et. al. n.d.). With the significant level of fructosamine in the blood, they need insulin and more medicines for combating hypertension than people with the genotype II. Fructosamin is then the substance resulting from the joining of fruit sugar and amine through chemical reaction and releasing water in the process. That substance is used as a detector of the blood sugar level and identify whether an individual has the tendency to have diabetes or not (Lavin 2009, p. 697). It was then proven by the study that patients with allele D have bad metabolic activity and exhibit cell damage development due to oxidative stress. The connection then between the treatment method and the genotype and hypertension treatment had small significance (Morhan et al. n.d., p. 16). Hypertension is then the drastic increase in the blood pressure that passes through the blood vessels and result to tearing of the walls of the vessels. Its complications are heart attack, kidney failure and stroke (Cohen 2004, p. 9). The amount of fructosamin in the bodies of the patients was then affected by inhibitors as its presence reduced the amount while its absence allowed the prevalence of beyond the normal level of fructosamin seen in the body. The study concluded with the patients having resistance to taken insulin led to a degrading state of metabolism that resulted to oxidative stress (Morhan et. al. n.d., p. 16). The study showed how certain genes affect the condition of diabetics. Going on with the oxidative stress, it becomes a complication of diabetes once superoxide has been made in excess through the existence of hyperglycaemia. It happens in detail as such overproduction of superoxide leads to higher levels of nitric oxide creating strong oxidants that hastens the appearance of complications from diabetes. The same method also causes damages to the inner linings of the blood vessels for diabetic patients (Morhan et. al. n.d., p. 17). Hyperglycemia then is the condition of having high concentration of glucose in the blood as a result of not having much insulin in the body to regulate the blood sugar levels. It may progress slowly or may come out abruptly that may pose serious complications. When it goes out of control, it has the ability to dehydrate the person and experience severe chemical imbalance in his body. It is then usually related to diabetes ...Download file to see next pagesRead More
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