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CVD Proposal Prrofreading - Essay Example

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2. Abstract Diabetes is currently among the fastest growing debilitating disease in the world. In year 2007 United Arab Emirates (UAE) was ranked second country in the world with in regard to prevalence of. Latest study carried out by specialist in Al Mafraq hospital sponsored by WHO revealed that 26% of UAE nationals suffer from diabetes, and that 40% of those aged 60 years and above suffer from the disease with cardiovascular (CVD) complications…
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CVD Proposal Prrofreading
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Download file to see previous pages Our long term goal is to utilize the outcome of the study in individualization of drug therapy and diagnosis of T2D with CVD bases on the genetic profile of patients from Arab Population. This would result in substantial improvements in quality of life of the affected individuals and a reduction in healthcare costs. Identification of target genes may also lead to development of novel therapeutic modalities. Furthermore, the characteristics of Arabic population make them ideal for the genome wide study of diabetes, a complex, polygenic, multi-factorial disorder. 3. Relevance It is hoped that this proposed study will pave way in identifying susceptibility genes for the Type 2 Diabetes with CVD in UAE population moreover. It will assess if genetic profiling could be used successfully to identify high-risk individuals, this would result in substantial benefits to both individuals and society. ...
4. Project Personnel Dr. Habiba alsafar is the lead investigator on this program and will dedicate 1.2 calendar months approximately 10% of her time overseeing the project. Dr. Nicolas Christoforou is a molecular-cell biologist and an academician at KUSTAR and will, he will avail essential tools in all aspects of molecular biology. He will also provide training and supervision to interns. Dr. Christoforou will dedicate 0.8 calendar months, approximately 8% of his time supervising the project. Dr. Ahsan Khandoker will dedicate 0.5 calendar months i.e. approximately 5% of his time preparing tools in the assessment of cardiac autonomic function for this study. Dr. Maher Maalouf from Industrial department in KUSTAR is planned to dedicate 0.5 calendar months approximately 5% of his time providing valuable support and consultative advice regarding statistical methods and analyses of the project KUSTAR nominees have also invited Drs. Ahmed Hasson to be a co-investigator in this study. He is a consultant Endocrinologist and chairman of Research & Medical Education from Dubai Diabetes Center in Dubai. Dr Ahmed will contribute as clinical expert, access to T2D patients with CVD and provide guidance on clinical matters. 5. Objectives and Goals This proposal present plan to initiate a seed project in the United Arab Emirates (UAE) particularly in Abu Dhabi with an aim of identification of genetic associated with Type 2 Diabetes resulting to development of cardiovascular disease (myocardial infarction) among Arabs in UAE. Furthermore, address genetic diversity in UAE providing insight into mechanisms that cause this disease. These developments could possibly lead to improved intervention and prevention programs to improve quality of life throughout UAE and ...Download file to see next pagesRead More
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