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Assessing non-parametric or t tests - Assignment Example

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Critique of a t-test used in a research article FirstName LastName MN 503, Kaplan University 21/11/2012 Critique of a t test used in a research article INTRODUCTION The purpose of this paper is to critique the t test of the research article ‘The Effects of Vitamin B6 on the Liver of Diabetic Rats: A Morphological and Biochemical Study’ done by Sehnaz Bolkent, Ozlem Sacan, Ayse Karatug and Refiye Yanardag…
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Download file to see previous pages Student’s t-test for single mean is used to test a hypothesis on a specific value of the population mean. It is used to test the null hypothesis against the alternative hypothesis. The t-test for difference of means is used to test the hypothesis that two populations have the same mean. A paired t-test is usually used when the two samples are dependent- this happens when each individual observation of one sample has a unique relationship with a particular member of the other sample. A t-test for correlation coefficient is used for testing an observed sample correlation coefficient (r).Lastly, a t-test for testing significance of regression coefficient is used to test the significance of regression coefficients in linear and multiple regression setups. However no matter the type of t-test you use two assumptions have to be met. These assumptions are that the populations from which the samples are drawn are normal and the population standard deviation is not known. In this research article unpaired t-test was used. Unpaired t-test which is also known as the student's t-test assumes that analyzed data is from a normal distribution. An unpaired test will need two independent groups to be applied and the sample size from the two groups may or may not be equal. In addition to the assumption that the data is from a normal distribution, there is also the assumption that the standard deviation (SD) is approximately the same in both groups. BRIEF DESCRIPTION OF THE STUDY The research study is ‘The Effects of Vitamin B6 on the Liver of Diabetic Rats: A Morphological and Biochemical Study’ which was done by Sehnaz Bolkent, Ozlem Sacan, Ayse Karatug and Refiye Yanardag. It is a biological study where the aim of the research study was to examine the morphological and biochemical results of supplement B6 on liver organ cells of normal and streptozotocin-diabetic mice. A trial diabetic issue was caused by intraperitonal hypodermic injection of streptozotocin (STZ) in a single amount of 65 mg/kg. Vitamin B6 was applied by subcutaneous hypodermic injection at an amount of 20 mg/kg for 15 times. The degenerative changes in the liver organ cells, biochemical changes in sugar stages and in serum aspartate transaminase (AST), alanine transaminase (ALT) and alkaline phosphatase (ALP) actions were identified. Degenerative changes were seen in the suffering from diabetic issues creatures by light microscopic research. Blood vessels sugar stages, serum AST, ALT and ALP actions improved in the suffering from diabetic issues group. On the other hand, the treatment with supplement B6 for 15 times changed these results. As a result, all of the acquired morphological and biochemical results led to the summary that supplement B6 has a safety effect against diabetic issues. DESCRIPTION AND CRITIQUE OF THE STATISTIC The biological results in this study were evaluated using unpaired t-test. The two variables used were control and control animals given vitamin B6. Both variables were subjected to the same conditions for a specified time of 15 days. The function unpaired test is used to compare two population means. Basically the main aim of this function is to test the null hypothesis that the two population means are equal or the same. The procedure to carrying out an unpaired t-test is first you have to calculate the difference between ...Download file to see next pagesRead More
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