The aim of this essay is to examine critically the article of Serefhanoglu and colleagues (2006) about their clinical experience with three combination regimens to manage high-risk febrile cases of neutropenia. …
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Using the current best evidence is a key practice of science; therefore, research articles must be read critically. Although it is not a simple process; however, it is an essential skill to develop to explore research results in an independent way. Transmission of best practice is the first step in the process of application evidence of best practice in patient care, bridging the gap between evidenced best practice and reality practice. In addition, critical reading changes attitudes and perceptions of utilizing research (Shankar and Subish, 2007). A structured framework for an article critique is a tool that brings about questions leading to better assessment of the value of a research paper. The primary aim of the structured framework is to question each section of the paper to achieve analysis then better understanding of the content (Branson, 2004). The aim of this essay is to review critically the article of Serefhanoglu and colleagues (2006) about their clinical experience with three combination regimens to manage high-risk febrile cases of neutropenia.
2. ARTICLE CRITIQUE
The article of Serefhanoglu and colleagues (2006) is an example of a quantitative research design that produces statistical data from numerical results aiming at generalization of findings (Dawson, 2002). The authors managed 89 febrile episodes (in 62 cancer patients with neutropenia) with ceftazidime and amikacin in 29 episodes, a combination of piperacillin, tazobactem and amikacin in 30 episodes, and meropenem combined with amikacin in further 30 episodes. The authors inferred all three regimens were safe and effective as empirical treatment for high-risk febrile neutropenia patients.
Research articles' titles are either descriptive or conclusive (briefing the authors' inferences); however, in any case, it should be clear enough to pass on the research theory and methods (APA publication manual, 2001). The title of the article at hand is descriptive and explains the objective of the research.
2.2 Authors, date, and key words
It is of importance to examine how relevant the authors' institutional affiliation to the subject of the paper as it gives credibility to their experiences (Dawson, 2002). Choosing article key words is not just an author preference, but to further search easier, they must appear in the medical subjects list of the National Library of Medicine at http://www.nlm.nih.gov/mesh/MBrowser.html (Branson, 2004). The institutional affiliation of the article authors is relevant to the subject; besides, the key words selected appear in the medical subjects list.
Abstracts became an important part of a research article since electronic databases are a primary method of finding relevant research. Abstracts can be informative composed of a single paragraph describing everything relevant to the article; alternatively, they can be indicative, structurally describing the article contents (Derntl, 2003). The abstract of the article at hand is an indicative, well-structured, content-informative abstract. Thus, the article's abstract is reflecting the experimental design and results of the research.
2.4 Introduction, research problem, and research questions
The introduction section is the part of a research article that enlightens the reader with the outline of the subject addressed. Thus, it should have three identifiable parts, a
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