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Effect Disorders Have on Adult Neurogenesis - Research Paper Example

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Neurogenesis has been linked with hippocampal-dependent functions such as the learning and memorization of explicit information as well as emotional response. Most factors that have a positive influence on the proper functioning of the hippocampus such as treatment of depression…
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Effect Disorders Have on Adult Neurogenesis
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Download file to see previous pages Therefore, neurogenesis normally leads to production of new neuronal cells that serves to provide an additional stock of plasticity to allow the adult brain to adapt to changing environmental cues. This in the end provides the possibility of making stable modifications between the existing neuronal network and its cognitive and emotional functions.
Winer, Kohl and Hage present that the generation as well as cell death of a cell of a newly generated tissue, plays a significant role in the development and maintenance of the brain of both adults and embryos. Consequently, any alterations in such processes are normally seen in the presence of a neurodegenerative disease. There are a number of such diseases that that tend to interfere with the proper functioning of the brain and other associated neurological functions. These diseases include Alzheimer’s disease, Schizophrenia, Epilepsy and Depression. This paper seeks to analyze the various effects of that these disorders have on adult neurology. Moreover, the precise effect of each of these disorders will also be highlighted with particular interest on the specific part of the brain the disorders tend to affect.
According to Scharfman, in the adult brain neurogenesis usually occurs in three distinct areas, the subventricular zone, the olfactory bulb and the dentate gyrus of the hippocampus. Winer, Kohl and Gage document that disorders that tend to interfere with the proper neurological functioning of the adult brain, are associated with certain genes that play a great part in the development of the disorders. Some of these genes include presenilin, and alpha-synuclein. They tend to have some psychological effect in the modulation of the plasticity of the brain especially on protein membranes and areas with a high concentration of synapses. Additionally, the alpha-synuclein gene also tend to interfere with the synthesis of dopamine, whose synthesis, metabolism, subsequent release or ...Download file to see next pagesRead More
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