Contact Us
Sign In / Sign Up for FREE
Go to advanced search...

Insulin - Term Paper Example

Comments (0) Cite this document
The hormone is released in the body when there is an elevated level of glucose in the blood plasma. Upon its release in the blood stream, the…
Download full paperFile format: .doc, available for editing
GRAB THE BEST PAPER92.7% of users find it useful
Read TextPreview

Extract of sample "Insulin"

Download file to see previous pages The termination of gluconeogenesis and glycogenolysis results to restoration of normal glucose levels in the blood. The action of insulin in the body is usually brief and the level blood sugar changes after the action of insulin subsides. Besides the control of blood sugar, production of insulin initiates a series of metabolic reactions that are mainly mediated by the changes in expression of over 100 genes in the body (O’Brien and Granner, 1117). One of the major effects of insulin in such physiological processes includes the regulation in the expression of genes that stimulate absorption of amino acids, metabolisms of lipids mainly in the muscles and adipose tissue. In addition, insulin affects the expression of genes used for growth, development and survival of somatic cells (Rhodes and White8)
Alfred Sanger did the first sequencing of amino acids that make up insulin hormone in 1955 (BCBC 1). According to BCBC (1) insulin is the first protein to have its amino acid chain determined and sequenced. Moreover, the hormone is the first “peptide protein measured by radioimmunoassay technique”. In addition, insulin is the first hormone to be produced in microorganisms using recombinant DNA technology, a process that was successfully conducted in the 1970s. Since then, insulin produced by recombinant DNA technology has been used for treating diabetes, replacing earlier hormones that were produced from purification of insulin from animal species (BCBC1)
Disruption of insulin synthesis in the body causes several physiological changes in the body. One of the major impacts of low glucose production is hyperglycemia, a medical condition characterized by an abnormal increase of glucose in the blood plasma (Steiner and James 42). Other effects include poor growth and development of the body. Diabetic patients ...Download file to see next pagesRead More
Cite this document
  • APA
  • MLA
(“Insulin Term Paper Example | Topics and Well Written Essays - 1750 words”, n.d.)
Insulin Term Paper Example | Topics and Well Written Essays - 1750 words. Retrieved from
(Insulin Term Paper Example | Topics and Well Written Essays - 1750 Words)
Insulin Term Paper Example | Topics and Well Written Essays - 1750 Words.
“Insulin Term Paper Example | Topics and Well Written Essays - 1750 Words”, n.d.
  • Cited: 0 times
Comments (0)
Click to create a comment or rate a document


Insulin (pancreas/type II diabetes)

... of the of the Concerned Health Sciences and Medicine 2 May Insulin pancreas type II diabetes Introduction Globally, 346 million people suffer from diabetes and World Health Organisation (WHO) estimates that mortality rates due to diabetes will double between 2005 and 2030 (WHO 2011). In England, the prevalence of diabetes in 2009/10 was determined to be 4.3 per cent (NHS 2011). Diabetes mellitus (DM) type 2 is a lifestyle linked metabolic disorder, with multiple aetiologies, in which the main abnormality is chronic hyperglycaemia. Hyperglycaemia can result from defective secretion of insulin, insulin action or both (WHO 2006; ADA 2012). Chronically elevated blood glucose levels lead to various metabolic disturbances, organ damage... and...
6 Pages(1500 words)Essay

Stem Cell Research- Using stem cells from Testes to produce Insulin for Type 1 Diabetics

...? Using Stem Cells from Testes to Produce Insulin for Type Diabetics (first, middle,last) Diabetes is perhaps the most deadly disease known. According to World Health Organization (WHO), in the year 2000, 171 million people were living with the disease and predict that this count will be doubled by 2030. There are different types of diabetes. Type-1 diabetes is one of them and found mostly in children and young adults. It is due to a malfunction by one’s own immune system that destroys beta cells in pancreas and stop producing insulin, required to process the food. There are conventional treatments available but they do not cure the disease. Now, scientists have given some hopes to the disease stricken...
4 Pages(1000 words)Research Paper

Research the principles of insulin production via genetic engineering

...?Principles of Insulin Production through Genetic Engineering I Introduction Insulin is an important hormone because it plays a big part in maintaining sugar level homeostasis in the human body. The inability of the body to control its sugar level will result in hyperglycemia, which can lead to diabetes mellitus. Certain types of diabetes mellitus require intensive insulin therapy because the physiological mechanism for insulin production is malfunctioning. In the past, insulin production was very difficult because they needed to be extracted from hundreds of slaughtered animals just to treat one patient. Today, however, insulin is...
5 Pages(1250 words)Essay

Nurse-Led Implementation of an Insulin-Infusion Protocal in a Gender

...? Nurse-Led Implementation of an Insulin-Infusion Protocol in a General Intensive Care Unit Nurse-Led Implementation of an Insulin-Infusion Protocol in a General Intensive Care Unit The title of the research clearly identifies the type of study used for the case, which is an experimental one, as the title points out that nurses are to implement the safe and effective protocol. The major populations covered by the study are clear from the title, as it points out non-diabetic ICU patients and nurses, as the implementers. The study was carried out to solve the incidences of hypoglycemia among ICU patients, due to the usage of a strict glycaemic control (SGC), which is noted as having caused the death of ten patients. The problem... is an...
3 Pages(750 words)Research Paper

Interaction of Brain and Insulin

...? Physiology Research Paper Physiology Research Paper The brain has been considered to be a principal target of insulin actions among human being due to its insulin sensitive tissues; in fact, this is also attributed increasing evidence regarding insulin receptor signaling. In this case insulin receptor, signaling is expected to facilitate neuronal surviving and the regulation of food intake. There is a profound expression of insulin receptors in the brain; in fact, they have a high density in hypothalamus, hippocampus, and cerebrocortical tissues, whereby they undertake distinct functions and promote tyrosine phosphorylation of proteins (Ketterer,...
4 Pages(1000 words)Research Paper

Gene Knockout Methodology and Insulin Action

...26th Feb 2007 Gene Knockout Methodology and Insulin Action Gene knockout methodology has been useful in gaining further understanding on the cellular basis of insulin action. Gene knockout is a term given to an organism that has been genetically engineered. This organism has in its chromosomes one of more genes that has been engineered to be non-functional or knocked out, mainly for research objectives. The organisms are called knockouts and are used to discover more about a sequenced gene whose function is not completely known or understood. By comparing these knockout organisms with normal ones, researchers can learn more about its behaviour or functioning in the gene's absence. Gene knockout...
5 Pages(1250 words)Essay

The Insulin Resistant Diet

...The Insulin Resistant Diet: Why and How Diabetes is increasing at an alarming rate and is a serious health risk to millions of people nationwide. According to the Center for Disease Control (CDC), "diabetes among adults increased rapidly during the 1990s across all regions, demographic groups and nearly all states in the United States" (Center for Disease Control, 2000). While this epidemic has affected all age groups, the age group of 30-39 is especially problematic with a 70 percent increase during the eight period of 1990-1998 (Center for Disease Control, 2000). These startling statistics were accompanied by a dramatic increase in obesity, adult onset diabetes, and numerous other chronic diseases. Researchers have...
2 Pages(500 words)Assignment

Insulin-Dependent Diabetes Mellitus

...BIO 271 Colleen Williams April 2008 Insulin-dependent diabetes mellitus (IDDM) IDDM, an autoimmune disease usually begins in childhood or young adulthood. This kind of diabetes is more common in females than in males and is the most common form of diabetes. In USA, IDDM is responsible for only 5 percent or less for causing diabetes. IDDM causes more impact on life compared to non-insulin-dependent diabetes (NIDDM). Also known as type I diabetes, juvenile diabetes and diabetes mellitus. (Condition: Insulin dependent Diabetes mellitus, 2008) IDDM is caused by a reaction caused in the body such that the immune system looses the capability of insulin-secreting cells in the...
5 Pages(1250 words)Assignment

The truth about Rotating Insulin Injection Sites : How they can make a big difference

...THE TRUTH ABOUT ROTATING INSULIN INJECTION SITES: How they can make a big difference Diabetes mellitus is defined as a disease in which the pancreas fails to secrete adequate levels of insulin to accommodate blood glucose levels. (FUNDAMENTALS OF NURSING: Standards and Practice, by Sue C. Delaune and Patricia K. Ladner) Due to the failure, insulin injections are necessary for diabetic care. In addition, there are a wide range and variety of complications arising from the disease. These lead to the close monitoring of the factors that affect insulin administration, including rotating insulin injection sites. FEELINGS: There is a patient who was...
2 Pages(500 words)Essay

Recombinant Human Insulin

...Recombinant Human Insulin Insulin is a hormone that is secreted by a group of cells called as islets of langerhans which is located at the pancreas. The pancreas produces many digestive enzymes and hormones. After a good meal, the stomach receives a variety of nutrients like carbohydrates, fats, proteins and minerals. Among them the carbohydrates are absorbed in the intestines and these carbohydrate moves into the blood stream as glucose. The insulin after the secretion from the pancreas moves into the blood stream and gets attached to the insulin receptors that are present in most of the cells. Thus insulin circulates in the blood stream. The cells...
20 Pages(5000 words)Research Paper
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.

Let us find you another Term Paper on topic Insulin for FREE!

Contact Us