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Genetically Modified Foods - Research Paper Example

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This paper entitled "Genetically Modified Foods" deals with the impact of genetically modified food. As the author puts it, the genetic manipulation of foods is one of the most divisive issues in the area of food production all over the world. …
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Genetically Modified Foods
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Genetically Modified Foods: Good for the World, or an Eco-Disaster Waiting to Happen? Introduction The genetic manipulation of foods is one of the most divisive issues in the area of food production all over the world. While many are in favor of producing and using genetically modified (GM) foods, there is a growing multitude who vehemently oppose GM foods. The global debate on GM foods encompasses all societies and people from every socio-economic status (Daunert et al: p.327). Through the process of selective breeding, “fruits of exotic taste, roses with specific colors and fragrances, and chickens that lay eggs that are lower in cholestrol content” (Daunert et al: p.327) have been developed. The process is considered as harmless genetic manipulation when there is no inter-species crossing, and the technique is limited to improving a species with a trait that is native to the particular species. However, with the arrival of biotechnology, genetic modification and selective breeding became more precise, with genetic manipulation focusing on specific genes that were not indigenous to the species. Improvements to already elite varieties were carried out by introducing new traits. For example, inter-species crossing has enhanced traditional crops by the breeding of insect-resistant and increased nutritional value corn and rice respectively. This modification of the species followed by the creation of genetically modified foods has been a globally controversial issue (Daunert et al: p.327). The purpose of this Memorandum is to discuss the pros and cons of the arguments in favor of and against genetically modified foods. The primary strengths and weaknesses of the two sides will be identified, the more persuasive argument of the two will be determined and examined, and recommendations and solutions will be suggested for optimal future outcomes. Overview of the Arguments Pro and Con Regarding Genetically Modified Foods History reveals that the genetic modification of food has been carried out since several centuries, for both plants and animals. The well-known geneticist Gregor Mendel is known to have performed genetic manipulation in the 19th century which later developed into selective breeding practices. The reasons for supporting genetically modified foods are related to obtaining higher levels and better quality production of agricultural and animal products. This is required for combating human malnutrition and world hunger through increased and more substantial crops with improved nutritive values. On the other hand, the reasons for countering it are related to its adverse effects on human health such as allergies, besides hazardous inter-species gene transfer and potential negative environmental and ecological changes (Daunert et al: p.327). The Business Aspects of Genetically Modified Food International trade and U.S. domestic politics not only deal with domestic regulation on competitive trade, but also on the obstacles to trade that are presented by differences in related regulations of the governments of various nations. The transatlantic dispute over genetically modified food is due to the diversity in opinions regarding the benefits of the new development (Young: p.460). Firstly, the impact of foreign rules on U.S. agricultural producers is mitigated because in the case of most crops, domestic consumption is given priority over exports. Secondly, the European Union (EU) is the third largest export market for the U.S., while the more significant export markets Canada and Japan have less restrictive approaches to agricultural biotechnology than the EU. Even so, it is the EU’s rules that have the strongest influence on the United States. Thirdly, policy change works out very high in cost, mainly because genetically modified foods are required to undergo a process of approval, instead of having to comply with a particular standard. This means that instead of changing a particular standard which results from the regulatory process, trading up through changing the regulatory process itself would have to be done. For this purpose, domestic institutions rather than outcomes would have to change, though the former are highly resistant to change (Young: p.461). Further, GM crops are subject to an approval process, hence exported products require the approval of the importer. Domestic regulator changes do not help to acquire access to the foreign market. Moreover, an additional complication is that genetic modification is considered to be a production process, according to the U.S. government. “The dynamics of trading up tends to be weaker with regard to rules regulating production processes, such as standards for emission from factories” (Young: p.461). Most of the process measures impose costs on domestic producers, putting them at a disadvantage compared with foreign competitors. On the other hand, the European Union deals with genetic modification as though the scientific process affects the character of the resulting products, due to which the EU impedes trade of GM foods (Young: p.461). Figure 1. Increase in World Croplands Used for Genetically Modified Crops (ITM Online, 2009) From Figure 1. given above, it is clear that the area devoted to growing biotechnology crops all over the world has risen steadily since 1996 until 2003. Genetically modified food crops include the well-known “roundup ready” soybean introduced commercially in 1997. These crops were developed by the firm Monsanto, that produced genetically modified canola and manufactures the herbicide termed “Roundup”, a derivative of glyphosphate. The crops are not adversely impacted by the weed killer. Other crops grown commercially are sweet potato resistant to a powerful virus with the potential to destroy most of the African harvest; rice with greater content of iron and vitamins to help overcome chronic malnutrition in Asia, and a number of plants with the capability to survive weather extremes. “There are over 100 species of plants in the testing phase for potential commercial use of their genetic modifications” (ITM Online, 2009). Though these genetically modified crops are increasingly relied upon, they form only a small part of the entire farming activity. In 2003, about 167 million acres were used for growing transgenic crops, representing about 4.5% of the global cropland. Seven million farmers grew these crops in 18 countries, with the main GM farming carried out in the “U.S., Argentina, Canada, Brazil, China, and South America” (ITM Online, 2009). Figure 2. Extent of Transgenic Crops Production in Various Countries (ITM Online, 2009) Figure 2. given above represents the breakdown of the levels of main transgenic crop production in various countries: the United States: 63%, Argentina: 21%, Canada: 6%, Brazil: 4%, China: 4%, and South Africa: 1%. In the graph above, the acreage in millions is also given for the countries indicated. It is believed that in industrialised countries this commercial enterprise will level out, whereas in developing nations it will rise up for the next several decades. GM product development through research is likely to increase in the next few years, with greater access to genetic information and resources (ITM Online, 2009). The Primary Strengths and Weaknesses of the Issue One of the main strengths of the argument in favor of genetic modification of food (GM) is that there is extensive improvement in the quantity of crop yield, while at the same time the need for fertilizers and pesticides is considerably reduced. However, the disadvantage is that such agricultural yield are inadequately tested, and may cause unknown dangers to health. Hence, though farmers and the public in poor, developing countries will benefit greatly from improved crops production, environmentalists are creating barriers to the genetic modification of food. According to Singh et al (p.602), genetic or transgenic modification applied to plant and animal food sources have a great potential for improving human nutrition and health; however, it is essential that facilities for growing GM crops are available in the developing as well as the developed world. Concurrent with the benefits of genetic modifications of plants there are potential risks, which is common to all technologies. New gene combinations with novel traits for example resistance to pests, diseases, and herbicides are created by means of both traditional plant breeding methods as well as transgenic techniques; however greater genetic novelty may be possible by the latter method (Singh et al: p.602). The environmental benefits obtained from introducing GM crops are as follows: Crop production cost is reduced and yield is increased. For example, some of the transgenic crops such as cotton, corn, soyabean, and maize reduce crop production cost and increase the yield. A genetically modified (GM) crop developed by Monsanto is “Bt cotton that produces an insect control protein (Cry1Ac) derived from the naturally occurring soil bacterium, Bacillus thuringiensis” (Singh et al: p.602). Production of the protein in the cotton plant ensures protection against Lepidopteran insect pests including cotton bollworm and pink bollworm, according to Betz et al (p.156). On the other hand, the production of unexpected proteins may take place, since genetic engineering is not very accurate, and this may be toxic or allergenic for humans. Similarly Bt maize varieties require considerably reduced insecticide, greater control of target insect pests, increased yield, lower production costs, improved profitability, lower farming risk, and greater opportunity to grow the crop, leading to beneficial outcomes in the form of higher profits for the farmers (Carpenter & Gianessi: p.24). According to Govil (p.415) there is a decrease of over 16 million pounds of insecticide used per year, in the production of Bt maize varieties, as reported by the National Center for Food and Agricultural Policy in Washington, D.C., in the U.S. Hence, it is clear that there is an enormous decrease in pesticide use with corresponding improvement in the environment, and a radical increase in productivity and savings in production costs. At the same time, genetically engineered plants can cause contamination of plants through cross-pollination by pollen carried by the wind. Reducing toxic chemicals in the environment is one of the greatest benefits of reducing the use of chemicals for pest control. This is because, transgenic crop plants such as soybean, corn, canola and cotton contain pest resistant genes, and are immune to attack from specific pests. The use of several hundred million pounds of pesticides by U.S. farmers had every likelihood of poisoning the soil, air, ground water, and aquatic ecosystems, states Brown (p.52). Contrastingly, it may so happen that genetically engineered plants become potentially invasive, and hence detrimental to human and animal health. Environmental monitoring and remediation is being carried out in recent years as a method of clean-up, and is being investigated scientifically. According to Monciardini et al (p.2761), transgenic plants are a tool for detecting and dealing with environmental pollution. Several plant taxa are capable of metal phytoextraction or organic compound phytodegradation. Through genetic manipulation, specific processes for further improvement can be identified. For this purpose, genetic engineering of plants with non-plant transgenes increase phytoremediation outcomes against the priority pollutants such as organomercurials (Rugh: p.496). Research with transgenic plants helps to develop drug delivery systems and biopharmaceuticals for the treatment of life-threatening and chronic diseases (Fischer et al: p.820). On the other hand, genetic engineering may result in resistance to antibiotics. There are chances for biopiracy to occur, with genes of plants and animals stolen from developing countries. Moreover, there may be moral objections to genetic engineering since it is unnatural. An important issue is that, the downsides of genetic engineering should not result in depriving poorer nations from the advantages of the technology. The opponents of GM foods include the special interest groups such as Greenpeace, Friends of the Earth, and the Organic Consumers Association, as well as several public figures (Daunert et al: p.328). It is important to note that the activists against GM foods base their opposition on philosophical ideals rather than scientific or economic principles. GM food production is supported by great corporate houses such as Monsanto, Syngenta, and DuPont-Pioneer. Activist groups such as Greenpeace fear that farmers who grow GM crops will become dependent on these companies. According to an IMF News Brief (2002), several African countries are facing dire food shortage, especially Eritrea, Ethiopia, Lisotho, Malawi, Mozambique, Swaziland, Malawi, and Zimbabwe. Even so, their governments have hesitated to import genetically modified grain especially in Zambia, although suppliers have offered to provide the grain in the form of flour. It is essential that alternative sources to GM grain need to be investigated urgently for the poor nations. Evaluation of the Side which is More Persuasive: The Negative Aspects of GM Several issues related to health, environment, economic aspects, consumer and strategic problems arise from the use of genetically modified foods. Hence, the downsides of using GM foods appear to be more persuasive, and clearly indicate that the technology should be sparingly used, and only in circumstances where it is most required, and under optimal conditions. An evaluation of the adverse outcomes and risks of using genetically engineered food relates to the ecology and toxicology of GM crops, and the main issues of sustainability, globalisation, ethics, and socioeconomics. 1. There is the potential risk of introducing allergens into recipient plants through genetic engineering, and thus into foods, state Nordlee et al (p.688). Testing for toxicity of food are required for monitoring proteins that are not found in the human diet. If the gene product is a known allergen, then it will be an allergen in a transgenic plant, also. Animal testing may also be required to determine whether there is an immune response in humans, particularly if the food will make a significant part of the diet (Harrison et al: p.728). Moreover, how protein structure relates to function, and the sensitising activity need to be further determined. 2. There are adverse effects on non-target species as well as on the environment. Transgenic crops that express insecticidal transgenes to control agricultural pests may also affect non-target organisms (Saxena et al: p.480). The toxic effect may be on organisms that are not pests of the crop itself, but are predators and parasites of pests, of benefit to agriculture. On the other hand, these problems may be directly related to the application of Bt toxin and not due to cultivation of crops carrying Bt gene, as observed in studies on the effect of spraying Bt-toxin on nontarget organisms as pests. 3. There is increased invasiveness and weediness of crop plants, which may result in agricultural weeds, and hence may add to the burden on farmers. This happens in crops such as Medicago sativa, Brassica napus, Brassica rapa, Helianthus annuus and Oryza sativa that have some weed like characteristics. To face the problem of the crop itself becoming weedier and invasive because of their transgenic and novel traits, herbicide mixtures are used to control the weeds (Bennett et al: p.273). 4. Pest resistance. The extensive cultivation of GM crops with pest or disease resistance has caused concern that this may impose intense selection pressure on pest populations to adopt the resistance mechanism. If insect pests become resistant to transgenic proteins, it may possibly limit the duration that an insecticidal transgenic variety can be feasibly grown. The first reported pest to develop resistance to Bt toxins applied as microbial formulations in open field populations, was the diamond black moth, states Tabashnik (p.12780). 5. The main issue that environmental activists have against GM crops is the fear for the loss of biodiversity. GM crops can be a threat to the crop diversity or may outgrow a local flora to the detriment of native species. Garcia et al (p.12338) studied the socio-economic and ethical implications of use of GM crops. Recommendations and Solutions It is evident that the pros and cons regarding use of genetically modified foods are almost equally balanced. The reasons why GM has more adverse effects than beneficial outcomes have been discussed above. According to Daunert et al (p.328), analytical chemists are required to make a signicant contribution to this issue. It was found that more methods are necessary, to allow rapid, sensitive and accurate measurements of genetically modified organisms. It is essential that current analytical methods should be adapted and new methods designed, which are able to detect transgenic DNA and newly produced proteins, in a cost-effective way. According to Daunert et al (p.322) these methods should be useful for performing analysis in untreated and processed food. Unapproved genetically modified organisms accidentally released in foods or feed should be detected, though their presence may be minimal. “Thus, a host of sampling strategies directed to detecting the presence of genetically modified organisms in foods in a sensitive, selective, and reliable manner should be developed and employed” (Daunert et al: p.328). The potential allergenicity of GM foods, also have to be taken into consideration. For this purpose, analytic chemists should develop reliable analytical methods for the rapid testing of possible allergenicity. This is an area of research that needs to be focused on in the future. It is essential to remember that proteins that are not allergic in the species of origin can become allergenic when transferred to a different species. Conclusion The pros and cons of the arguments in favor of and against genetically modified foods have been highlighted. The main strengths and weaknesses of the two sides were identified, and it was found that more than its benefits, the chances of an eco-disaster in the future was greater due to the production of GM foods. The negative aspects of using the new technology were discussed, and recommendations have been suggested for improving the benefits while reducing the chances for adverse outcomes. It is clear that the impact of genetically modified foods on U.S. trade is related to various factors such as domestic consumption being given priority over exports, and the European Union’s more restrictive rules applying to the U.S. export market rather than the more liberal policy adopted by Canada and Japan. Moreover, policy changes are not easy to carry out because the approval process that GM foods have to undergo require changing the regulatory process itself, impacting domestic institutions which are highly resistant to change. Hence, policy changes need to take into consideration the recommendations and solutions for improving the benefits of GM foods. Works Cited Bennett, R., Phipps, R., Strange, S., & Grey, P. Environmental and human health impacts of growing genetically modified herbicide-tolerant sugar beet: a life-cycle assessment. Plant Biotechnology, 2 (2004): 273-278. J-STAGE. Betz, Fred S., Hammond, Bruce G., & Fuchs, Roy L. Safety and advantages of Bacillus thuringiensis-protected plants to control insect pests. Regulatory Toxicology and Pharmacology, 32 (2000): 156-173. Elsevier. Brown, K. Seeds of concern. Scientific American, 284: 52-57. EBSCOhost Business Source Premier. Carpenter, Janet E. & Gianessi, Leonard P. Agricultural biotechnology: updated benefit estimates. Washington, D.C: National Center for Food and Agricultural Policy. (2001). Daunert, Sylvia, Deo, Sapna, Morin, Xenia & Roda, Aldo. The genetically modified foods debate: demystifying the controversy through analytical chemistry. Analytical and Bioanalytical Chemistry, 392 (2008): 327-331. Springer Standard Collection. Fisher, R., Twyman, R.M., Schilberg, S. Production of antibodies in plants and their use for global health. Vaccine, 21 (2003): 820-825. Elsevier. Garcia, S., Ezcurra, E., Schoel, B., Acevedo, F., Soberon, J. & Snow, A.A. Absence of detectable transgenes in local landraces of maize in Oaxaca, Mexico. Proceedings of the National Academy of Science of the United States of America, 35 (2005): 12338-12343. JSTOR. Govil, Suman. Biotechnology for environmentally sustainable development. Advanced Biotechnology, 200 (2004): 415-417. Elsevier. Harrison, L.A., Bailey, M.R., Naylor, M.W., Ream, J.E., Hammond, B.G., Nida, D.L., Burnette, B.L., Nickson, T.E., Mitsky, T.A., Taylor, T.A., Fuchs, R.L., & Padgette, S.R. The expressed protein in glyphosate-tolerant soybean, 5-enolpyruvylshikinate- 3-phosphase synthase from Agrobacterium sp. strain CP4 is rapidly digested in vitro and is not toxic to acutely gavaged mice. The Journal of Nutrition, 126 (1996): 728-740. Highwire Press. ITM (Institute for Traditional Medicine) Online. Issues surrounding genetically modified (GM) products. Institute for Traditional Medicine, Portland, Oregon. (2009). Retrieved on 27th July, 2009 from: http://www.itmonline.org/arts/gmo.htm IMF (International Monetary Fund) News Brief. IMF and World Bank issue a statement on the food situation in southern and eastern Africa. New Brief No. 02/ 123, International Monetary Fund, Washington, D.C. (2002). Retrieved on 28th July, 2009 from: http://www.imf.org/external/np/sec/nb/2002/nb02123.htm Monciardini, P., Podini, D., & Marmiroli, N. Exotic gene expression in transgenic plants as a tool for monitoring environmental pollution. Chemosphere, 37 (1998): 2761- 2772. Elsevier. Nordlee, J.A., Taylor, S.T., Townsend, J.A., Thomas, L.A., Bush, R.K. Identification of a Brazil-nut allergen in transgenic soybean. New England Journal of Medicine, 337 (1996): 688-692. E-Journal Website. Rugh, C.L. Genetically engineered phytoremediation: one man’s trash is another man’s transgene. Trends in Biotechnology, 22 (2004): 496-498. Elsevier. Saxena, D., Flores, S., & Stotzky, G. Insecticidal toxin in root exudates from Bt corn. Nature, 402 (1999): 480. Nature. Singh, Om V., Ghai, Shivani, Paul, Debarati, & Jain, Rakesh K. Genetically modified crops: success, safety assessment, and public concern. Applied Microbiology and Biotechnology, 71 (2006): 598-607. Springer Standard Collection. Tabashnik, B.E., Liu, Y.B., Malvar, T., Heckel, D.G., Masson, L., et al. Global variation in the genetic and biochemical basis of diamondback moth resistance to Bacillus thuringiensis. Proceedings of the National Academy of Science of the United States of America, 94 (1997): 12780-12785. JSTOR. Young, Alasdair R. Political transfer and “trading up”? Transatlantic trade in genetically modified food and U.S. politics. World Politics, 55.4 (July 2003): 457-484. JSTOR. Read More
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