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Biological Importance of Metal Complexes of Pyrimidine-2-Thione - Research Paper Example

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In the paper “Biological importance of metal complexes of pyrimidine-2-thione” the author examines 2-Mercaptopyrimidine nucleotides, which are present in the RNA of Escherichia Coli and the tRNA of yeast. 2-Mercaptopyrimidine nucleotides have been shown to inhibit tRNA synthesis…
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Biological Importance of Metal Complexes of Pyrimidine-2-Thione
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Download file to see previous pages Mo205L2(H2O)2.H2O (1)preparation. (5cm3)Aqueous solution of (NH4)2(MoO4) which is 0.24g and 1.0mmol respectively is added to LH solution in 25cm3 of EtOH (Speziale, 1963). The resultant slurry is subjected to heat, and the resultant solution, orange in color, is refluxed for duration of 4hours (Harris & Bertolucci, 1989). In this time duration, orange precipitate is realized (Foster & Snyder, 1963). The solid is then collected through filtration, immediately thereafter washed in 2cm3 of ethanol and diethyl ether, and then dried through vacuo (Wells, 1984). The yield is 35%, based on metal (Podson & King, 1945). Elemental analytical computation for the C8H16N8O10S2Mo: S, 10.00; C, 15.00; N, 17.50; H, 2.50%; illustrate that N, 17.51; C, 14.98; N, 17.51; H, 2.82; and AM(DMSO) 3 S cm2per mol (Greenwood & Earnshaw, 1997). W2O5L2(H2O)2.H2O (2) preparation (Anthony, 2007). This uses (NH4)2(WO4) and uses the same method applied in the first procedure (Peter, 2003). In this procedure, a bright yellow substance is isolated (Petricci et al, 2002). The yield is 50% metal based (Housecroft & Sharpe, 2005). The elemental analytical computation for C8H16N8O10S2W: H, 1.96; S, 7.85; C, 11.77; N, 13.73%, indicates that C, 11.62; S, 7.95; N, 13.77; H, 1.90%; and AM(DMSO) 2 S cm2per mol (Cotton et al, 1999).  In analyzing the antimicrobial activity; the bacterial strains were cultured in the nutrient agar slants (De Vito et al, 2005). ...Download file to see next pagesRead More
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