StudentShare
Contact Us
Sign In / Sign Up for FREE
Search
Go to advanced search...

Health Sciences - Study Contribution Review - Essay Example

Cite this document
Summary
Running Head: Study Contribution Review. Study Contribution Review Name:                              Institution:            Date: Introduction Epidemiological studies show that chronic heart failure (CHF) is one of the most prevalent problems in the developed world where it causes high mortality and morbidity…
Download full paper File format: .doc, available for editing
GRAB THE BEST PAPER98.4% of users find it useful
Health Sciences - Study Contribution Review
Read Text Preview

Extract of sample "Health Sciences - Study Contribution Review"

Download file to see previous pages

In spite of the interesting theoretical nature of working proposed for these drugs, most of them have not been of significant use in CHF (Van Gilst & Veldhuisen, 2003). Problem The lack of one perfect pharmacological treatment has been partly attributed to the probable effect of having used too many drugs within the extensive research regime that has characterized the search for effective CHF treatment. The too many ‘old’ and too many ‘new’ drugs make the attainment of an effective remedy through combination quite complicated because of the wide array of tries possible.

The large number of researches already carried out has led to the heightening of demands on new researches expected to deliver new options, thus posing even further challenges for any new researches (Van Gilst & Veldhuisen, 2003). Background The earliest pharmacologic treatment for CHF constituted a combination of diuretics and digoxin, but this was altered in the early 80s and the use of vasodilators started due to the hemodynamic concept. In the same decade (1987), ACE (Angiotensin converting enzyme) inhibitor enalapril was found to be more effective on reducing mortality (Blue & Stewart, 2001).

Additionally, it was also found to work well on asymptomatic left ventricular dysfunction. This option seemingly offered a good option of treatment, but prognosis remained poor and patients under its treatment were still asymptomatic. As such, research for new and better add-on drugs continued. The tried and tested included dopamine agonists, phosphodiesterase inhibitors, vasodilators and calcium antagonists (Van Gilst & Veldhuisen, 2003). Despite the short-term promising nature of these drugs, none was found to be of effective use in long-term trials that reviewed mortality.

Further studies proposed beta-blockers as the treatment in reducing mortality, especially when combined with diuretics and ACE inhibitors, with or without the inclusion of digoxin. Current study results show that the beta-blockers are effective in advanced CHF, and they could offer a 30% survival benefit when combined with ACE inhibitors. The next drug to be tested was angiotensin II receptor blockers (ARBs) (Van Gilst & Veldhuisen, 2003). This drug used the alternative path of blocking the receptor of angiotensin II instead of using inhibitor to block its production as an alternative solution.

The comparative use of ARBs and ACE inhibitors showed little difference in the long-run, thus implying none was effective. Other test options such as aldosterone receptor blockade reduced morbidity and mortality, but showed significant side-effects. Currently, numerous drugs such as eplerenone are under testing. Others under current testing include cytokine and endothelin antagonists and neutral endopeptidase inhibitors, but most of their short-term success has already been overshadowed by poor long-term results.

The search still continues, but as more new drugs are tested more confusion arises in the treatment regime (Feldman, 2006). Significance to cardiopulmonary care Given the above scenario practitioners should consider different strategies in CHF treatment, instead of increasing the number of drugs in the present regimen. A probable option may entail tailoring the therapy based on individual characteristics of the patient such

...Download file to see next pages Read More
Cite this document
  • APA
  • MLA
  • CHICAGO
(“Health Sciences - Study Contribution Review Essay”, n.d.)
Health Sciences - Study Contribution Review Essay. Retrieved from https://studentshare.org/health-sciences-medicine/1443923-study-contribution
(Health Sciences - Study Contribution Review Essay)
Health Sciences - Study Contribution Review Essay. https://studentshare.org/health-sciences-medicine/1443923-study-contribution.
“Health Sciences - Study Contribution Review Essay”, n.d. https://studentshare.org/health-sciences-medicine/1443923-study-contribution.
  • Cited: 0 times

CHECK THESE SAMPLES OF Health Sciences - Study Contribution Review

Ethical Expectations In Workplace

Philosophy is a great study that focuses on the analysis of an argument.... Philosophy and Ethics The research practice concerned with social sciences provides a suitable base for the analysis of social sciences.... Every individual person is supposed to observe and uphold a modicum of public morality....
8 Pages (2000 words) Case Study

Social Work Nursing Case Study

hellip; Studying social work is a very interesting and an intense exercise as it allows you to study the phenomenon of social work in different contexts.... A study at Master's level would definitely make a person to think and think hard about various issued related with this body of knowledge.... ne of the most important reasons that I wish to study to study for this profession is the fact that it provides a very accurate and true picture of how a person evolve over the period of time....
6 Pages (1500 words) Case Study

Environmental Impact - Life Cycle Impact Assessment

This is according to the “cradle to grave” study, which was conducted by the Abt Associates for the United States Environmental Protection Agency (EPA).... The study, which was conducted through a partnership involving the U.... However, there are some few notable areas in these Li-ion batteries that need to be improved in order to reduce possible public health and environmental impact....
7 Pages (1750 words) Case Study

Review article

Lewis (1966) employs the use of questionnaires that explore sociology, anthropology and psychology of the hundred families that are under study.... In the interest of analysing the culture of poverty in his home country, the study was conducted in Puerto Rico in a hundred slum dwelling families.... The questionnaires were centred family relationships, income and expenditure, personal and household possessions, friendship patterns, recreational patterns, politics, worldview, religion, health and medical history as well as openly ended interviews and psychological tests....
4 Pages (1000 words) Book Report/Review

The Contribution That Music Can Make to Health and Wellbeing

Music, health, and well-being: A review by Raymond and Macdonald (2013) asserts that musical participation as part of arts participation has a direct influence on the mental health and well being in people.... These positive emotions and feelings counteract the feelings and emotions of anxiety, stress People with mental health issues can benefit from music because it takes them away from thinking of themselves as patients by promoting their self-esteem, social recognition, confidence and status especially when they participate in singing (Bradt & Dileo, 2009:2, Music for stress and anxiety reduction in coronary heart disease patients)....
9 Pages (2250 words) Literature review

Behaviouralism as Valuable Approach to the Study of Politics

The author of this study under the title "Behaviouralism as Valuable Approach to the study of Politics" touches on the current issues concerning gender, religion, health and a point of contention is whether behavioralism is still a valuable approach to the study of politics.... The systematic study of politics was started by Greeks philosophers in the 4th century BC.... A German philosopher of the 19th century named Karl Marx introduced the Marxist approach which observes politics as a study of two conflicting social classes—the rich and the poor or the exploiters and the exploited....
8 Pages (2000 words) Case Study

Examining the Influence of Gender Inequality

This literature review "Examining the Influence of Gender Inequality" aims at concluding the extent of contributions made by individualization theses in understanding contemporary social relations, elaborating on the various facets of intimate life and family formations.... For instance, where on one hand, individualization theses have been quite significant in developing sociological understandings to the identification as well as the elaboration of the new paradigms of the contemporary society, its extent of contribution has also been limited owing to the lack of diversity and criticality in the discussions, especially in the cross-cultural context....
14 Pages (3500 words) Literature review

Stress and Its Relationship to Human Health

The "Stress and Its Relationship to Human health" paper start by identifying internal and external stressors followed by analyzing the anatomical and physiological explanation behind the effects of stress on human health.... It focuses on discussing the relationship between stress and human health.... hellip; Even though all these stress management techniques have been proven effective in the past, health care professionals should bear in mind that not all these techniques may equally work well for all patients....
11 Pages (2750 words) Literature review
sponsored ads
We use cookies to create the best experience for you. Keep on browsing if you are OK with that, or find out how to manage cookies.
Contact Us