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4.2 Technical Adequacy Analysis 15-164.3 Data Collection Process 164.4 Research Design 16-175. Conclusion 177. References 18-20 Introduction: Ethylene oxide is a sterilant gas, an important industrial chemical.(14) It is used as an intermediate in the production of ethylene oxide and is toxic, when inhaled.
There are reports of large health implications including respiratory disorders, dizziness, headache, and increase in exposure may also lead to convulsions, seizure and coma. It is rapidly taken up via lungs and can also be absorbed through the skin from the gas phase or from the aqueous solutions and is uniformly distributed in to the body as it is soluble in blood. Based on studies in occupationally exposed populations, ethylene oxide is a carcinogenic via inhalation route of exposure. Ethylene oxide causes leukemia, lymphoma, brain, hematopoietic and breast cancer.
It is classified as carcinogenic to humans by the International Agency for Research on Cancer.(14)Extensive research have been done to determine the toxicity of ethylene oxide through epidemiological studies, by exposing a cohort group of animals to ethylene oxide or on group of workers who have been. Ethylene oxide causes leukemia, lymphoma, brain, hematopoietic and breast cancer. It is classified as carcinogenic to humans by the International Agency for Research on Cancer.(14) Extensive research have been done to determine the toxicity of ethylene oxide through epidemiological studies, by exposing a cohort group of animals to ethylene oxide or on group of workers who have been working in environment containing ethylene oxide.(REF) This gas releases in to the atmosphere while handing, storage and transportation.
The present contribution discusses the health hazards of EtO in humans and environment. The physical and the chemical properties are also discussed. The potential exposures of this toxic gas in the environment (air, earth and water) and the occupational exposure and the routes of exposure (inhalation, skin and eye exposure and ingestion) are also discussed. The research methodologies pertaining to the occurrence of EtO is also described. Ethylene Oxide (C2H4O, EtO) is used as a sterilant in the pharmaceuticals and food industry(4).
It is used as a sterilant since its biocidal, both bactericidal and fungicidal.
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