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Critiquing Evidence - Essay Example

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This study “Critiquing Evidence” involves finding and critiquing evidence, selecting an article pertaining to the clinical question. This paper will critique an article “The effects of mild induced hypothermia on the myocardium: A systematic review” on the effects of mild induced hypothermia…
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Download file to see previous pages Cardiac arrest also causes neurological injury through several mechanisms. These mechanisms include reperfusion that leads to reoxygenation injury and perfusion failure which triggers cerebral ischemia. However, hypothermia can reduce the effects of reoxygenation and reperfusion. Hypothermia also decreases the cerebral metabolic rate for oxygen and provides protection against cerebral ischemia. Sometimes, mild induced hypothermia is considered beneficial to the myocardium. A small reduction of temperature affects the micro vascular blood flow in a drastic way. Several animal studies of AMI suggest that myocardial function can be improved through the mild induced hypothermia condition in the absence of cardiac arrest. However, not all the animal studies demonstrate a reduction in the myocardial damage after the induced hypothermia.  There are also several feasibility studies which have been performed on several individuals. These patients have undergone a primary PCI after a certain period, after the induction of hypothermia. These studies also faced certain limitations. Some of the limitations associated with the procedure include the use of less accurate techniques such as the nuclear imaging and measuring equipments. All the studies that have been performed till lately confirm that the effect hypothermia on neurological upshot after cardiac arrest has improved, hence; this has reduced the mortality rate. The authors also talked about some of the predicaments related to the study. ...Download file to see next pagesRead More
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