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Plasmodium Falciparum - Essay Example

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Plasmodium falciparum belongs to a Sporozoa class, which represents exclusively parasitic forms. Most of the Sporozoa representatives are parasitizing within the cells of various tissues of invertebrates and vertebrates as well as in human cells. This class is…
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Plasmodium Falciparum
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Download file to see previous pages The last is becomes infected in this way. All stages of malarial plasmodium development taking place in the body of the carrier – in a human, a bird and a mosquito. Such Sporozoa sporozoites are developed in the body of the mosquito and further transmitted to birds or human with saliva from the mosquito`s bite.
Life cycle and transmission. The life cycle of Plasmodium falciparum is associated with changes of hosts. One part of the life cycle takes place in the human body where the parasites reproduce asexually; the second part occurs in the body of a specific carrier of malaria – female mosquito Anopheles, where plasmodium reproduces sexually (Dantzler et al.). Therefore, for Plasmodium falciparum, the human is an intermediate carrier, and the female Anopheles mosquito is the final host. Infection by Plasmodium falciparum occurs during sucking blood of patients with malaria and then mosquito infects another person by introducing parasites with its saliva during the bite. Via infected mosquito`s saliva the sporozoites enter the bloodstream of host and within 30-40 min get into a place of primary localization – into the liver cells (Dantzler et al.). There takes place an intracellular parasite asexual reproduction called tissue (exoerythrocytic) schizogony. From each of sporozoites, a several thousand merozoites are formed. Further, they destroy hepatocytes and released into the bloodstream. The duration of this period is about 6-9 days. Merozoites penetrate into erythrocytes and thus begin the blood stage with trophosoite formation and erythrocytic schizogony (Wright and Rayner). In erythrocytes cells, the trophozoite is consistent passes through the ring, amoebic, mature trophozoite, schizont and merozoite stages. During schizogony, in erythrocytes occurs the formation of schizonts. Further, each schizont gives a rise to the several dozen of small merozoites ...Download file to see next pagesRead More
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